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Home > Understanding Breast Cancer > Breast Cancer Research > Table 5: Breastfeeding and breast cancer risk

  


Table 5: Breastfeeding and breast cancer risk

   

This summary table contains detailed information about research studies. Summary tables offer an informative look at the science behind many breast cancer guidelines and recommendations. However, they should be viewed with some caution. In order to read and interpret research tables successfully, it is important to understand some key concepts. Learn how to read a research table.

Introduction: There is solid evidence breastfeeding lowers the risk of breast cancer. Findings from large pooled and meta-analyses that combined data from many studies show women who breastfeed have a lower risk of developing breast cancer compared to those who do not [1-3].

A meta-analysis of five case-control studies found breastfeeding reduced the risk of both hormone receptor-positive (ER+/PR+) and hormone receptor-negative (ER-/PR-) breast cancers [4].

Learn more about breastfeeding and breast cancer risk.

Learn about the strengths and weaknesses of different types of studies

See how this risk factor compares with other risk factors for breast cancer.  

Study selection criteria: Large pooled and meta-analyses.  

Table note: Relative risk above 1 indicates increased risk. Relative risk below 1 indicates decreased risk.  

Study 

Study Population
(number of participants) 

Relative Risk of Breast Cancer in Women who Breastfed Compared to Women who Did Not
RR (95% CI)
 

Premenopausal 

Postmenopausal 

Pooled and meta-analyses 

Nelson et al. [1]

14 studies

0.87 (0.77-0.98)

 

Bernier et al. [2]

9 studies

0.76 (0.66-0.87)

0.83 (0.68-1.01)

CGHFBC [3]

147,275

0.94 (0.91-0.97)*

* For one year of breastfeeding

 

References  

  1. Nelson HD, Zakher B, Cantor A, et al. Risk factors for breast cancer for women aged 40 to 49 years: a systematic review and meta-analysis. Ann Intern Med. 156:635-648, 2012.
  2. Bernier MO, Plu-Bureau G, Bossard N, et al. Breast feeding and risk of breast cancer: a meta-analysis of published studies. Hum Reprod Update. 6(4):374-386, 2000.
  3. Collaborative Group on Hormonal Factors in Breast Cancer. Breast cancer and breast feeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50,302 women with breast cancer and 96,973 women without the disease. Lancet 20:187-195, 2002.
  4. Ma H, Bernstein L, Pike MC, Ursin G. Reproductive factors and breast cancer risk according to joint estrogen and progesterone receptor status: a meta-analysis of epidemiological studies. Breast Cancer Res. 19;8(4):R43, 2006.  

Updated 08/28/13