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Breast Cancer Risk Factors Table

 

The table below shows the relative risk of breast cancer for many factors. The relative risk compares the risk of breast cancer for people who have the factor to those who do not.
Factors are grouped based on the strength of the scientific evidence for each risk.

  • Established and probable have the strongest evidence behind them and are recognized as linked (or not linked in some cases) to breast cancer.
  • Possible factors have less evidence behind them; they suggest links to breast cancer but need more study before solid conclusions can be made.
  • Insufficient or inconsistent factors are backed by few studies or the studies to date show very mixed results, which don't allow comment on any potential link with breast cancer.

Click on any of the factors to learn more. 

Relative Risk Categories 

Strong increase  Moderate increase  Weak increase  No increase or decrease  Weak decrease  Moderate decrease  Strong decrease 

Established Factors

Recognized as linked (or not linked in some cases) to breast cancer. 


Risk of breast cancer for people with the factor compared to those without the factor  
Age  Strong increase in risk 
Being female  Strong increase in risk 
BRCA1 or BRCA2 gene mutation   Strong increase in risk 
Family history of breast cancer 
 

Strong increase in risk 

 

Moderate increase in risk 

High breast density  Strong increase in risk 
Hyperplasia (benign breast condition) 
  • Atypical
 

Strong increase in risk 

  • Usual
 

Moderate increase in risk 

Lobular carcinoma in situ (LCIS) Strong increase in risk 
Personal history of cancer (including invasive breast cancer, DCIS, Hodgkin's disease and other cancers) Strong increase in risk 
Radiation treatment during youth  Strong increase in risk 
Childbearing 
  • Not having children
 

Moderate increase in risk 

  • Having a first child after age 35
 

Moderate increase in risk 

High levels of blood androgrens (postmenopausal) Moderate increase in risk  
High levels of blood estrogens (postmenopausal) Moderate increase in risk 
Weight gain (postmenopausal) Moderate increase in risk 
Age at first period < 12 years  Weak increase in risk 
Age at menopause > 55 years  Weak increase in risk 
Alcohol consumption (one or more drinks/day) Weak increase in risk 
Ashkenazi Jewish heritage  Weak increase in risk 
Birth control pills (current or recent use only) Weak increase in risk 
Being tall  Weak increase in risk 
High socioeconomic status  Weak increase in risk 
Mammography (radiation exposure)  Weak increase in risk 
Postmenopausal hormone use (current or recent use only)
  • Estrogen only
 

Weak increase in risk 

  • Estrogen + progestin
 

Moderate increase in risk 

Body weight 
  • Premenopausal
 

Moderate decrease in risk  

  • Postmenopausal 
 

Moderate increase in risk 

Breastfeeding  Weak decrease in risk 
Abortion  No increase or decrease in risk 
Hair dyes  No increase or decrease in risk 
 

Probable Factors

Recognized as linked (or not linked in some cases) to breast cancer, although not as solidly as established factors.

Risk of breast cancer for people with the factor compared to those without the factor  
High bone density  Moderate increase in risk 
High levels of blood androgrens (premenopausal) Moderate increase in risk 
African-American ethnicity 
  • Premenopausal
 

Weak increase in risk 

  • Postmenopausal
 

No increase or decrease in risk 

Light at night and shift work  Weak increase in risk  
Physical activity 
  • Premenopausal
 

No increase or decrease in risk 

  • Postmenopausal
 

Weak decrease in risk 

Blood organochlorine levels (exposure to certain types of pesticides and industrial chemicals)  No increase or decrease in risk 
Breast implants  No increase or decrease in risk 
Electromagnetic fields (from utility wires, electric blankets, microwave ovens, fluorescent lighting, etc.)  No increase or decrease in risk 
Weight gain (premenopausal) No increase or decrease in risk 
 

Possible Factors

Recognized as potentially linked (or not linked in some cases) to breast cancer, but need more study before solid conclusions can be made.


Risk of breast cancer for people with the factor compared to those without the factor  
High levels of blood estrogens (premenopausal) Moderate increase in risk 
IGF-1 hormone levels 
  • Premenopausal
 

Moderate increase in risk 

  • Postmenopausal
 

No increase or decrease in risk 

Red-meat consumption 
  • Premenopausal
 

Weak increase in risk 

  • Postmenopausal
 

No increase or decrease in risk 

Vitamin D intake  Weak decrease in risk 
Aspirin use  No increase or decrease in risk 
Carotenoid intake  No increase or decrease in risk 
Dairy consumption 
  • Premenopausal
 

No increase or decrease in risk 

  • Postmenopausal
 

No increase or decrease in risk 

Deodorant/antiperspirant use  No increase or decrease in risk 
Dietary fat consumption  No increase or decrease in risk 
Fertility drug use  No increase or decrease in risk 
Fruit and vegetable consumption  No increase or decrease in risk 
Glycemic load/carbohydrate intake  No increase or decrease in risk 
Soy intake  No increase or decrease in risk 
 

Factors with inconsistent results or insufficient evidence

For these factors, there are few studies to date or results are very mixed. More research is needed to comment on any potential link to breast cancer.

Antibiotic use
Body care cosmetics containing parabens
Bras or underwire bras
Breast milk (having been breastfed as an infant)
Breast size
Caffeine
Cell phones
French fry consumption
Hair relaxers
In utero exposure to DES and breast cancer risk among offspring  

Left-handedness
Migraine headaches
Plastics
Secondhand smoke exposure
Smoking
Stress
Trauma to the breast 

 

Where do the data come from?

Human studies

The data in this table come from two main types of research studies: observational studies (prospective cohort or case-control) and randomized controlled trials. The goal of these studies is to give information that helps support or disprove an idea about a possible link between an exposure (like alcohol use) and an outcome (like breast cancer) in people. Although they have the same goal, observational studies and randomized controlled trials differ in the way they are conducted and in the strength of the conclusions they reach.

Learn more about different types of on research studies.

Animal studies

Animal studies add to our understanding of how and why some factors cause cancer in people. However, there are many differences between animals and people that make it hard to translate findings directly from one to the other. And, animal studies are designed differently than human studies. They often look at exposures in larger doses and for shorter durations than are suitable for people. Thus, animal studies can lay the groundwork for research in people, but in order to draw conclusions for human populations, we need human studies.

All data presented within the Understanding Breast Cancer section of this website come from human studies unless otherwise noted.  

Finding information on risk factors for breast cancer

Several organizations conduct research and/or prepare summary reports of research on certain exposures shown to have a link (or no link) to breast and other types of cancer. These agencies are a good place to find detailed, up-to-date information (for example, if you have concerns over a news item on cancer). The International Agency for Research on Cancer (IARC) is a part of the World Health Organization. The Centers for Disease Control and Prevention (CDC), the National Toxicology Program and the U.S. Food and Drug Administration (FDA) are all part of the U.S. Department of Health and Human Services. 

Updated 11/11/11