Vitamin B6 is a type of B vitamin. It can be found in certain foods such as cereals, beans, vegetables, liver, meat, and eggs. It can also be made in a laboratory. Vitamin B6 is used for preventing and treating low levels of pyridoxine (pyridoxine deficiency) and the "tired blood" (anemia) that may result. It is also used for heart and blood vessel disease; high cholesterol and other fats in the blood; high blood pressure; stroke; reducing blood levels of homocysteine, a chemical that might be linked to heart disease; and helping clogged arteries stay open after a balloon procedure to unblock them (angioplasty). Women use vitamin B6 for premenstrual syndrome (PMS) and other menstruation problems, "morning sickness" (nausea and vomiting) in early pregnancy, stopping breastmilk flow after childbirth, depression related to pregnancy, menopause, or using birth control pills, and symptoms of menopause. Vitamin B6 is also used for Alzheimer's disease and other types of dementia or memory loss, attention deficit-hyperactivity disorder (ADHD), Down syndrome, autism, diabetes and related nerve pain, sickle cell anemia, migraine headaches, asthma, carpal tunnel syndrome, night leg cramps, muscle cramps, arthritis, preventing fractures in people with weak bones, allergies, acne and various other skin conditions, and infertility. It is also used for dizziness, motion sickness, preventing the eye disease age-related macular degeneration (AMD), seizures, convulsions due to fever, and movement disorders (tardive dyskinesia, hyperkinesis, chorea), as well as for increasing appetite and helping people remember dreams. Some people use vitamin B6 for boosting the immune system, eye infections, cataracts, sleep problems, bladder infections, tooth decay, and preventing polyps, cancer, and kidney stones. Vitamin B6 is also used to overcome certain harmful side effects related to radiation treatment and treatment with medications such as mitomycin, procarbazine, cycloserine, fluorouracil, hydrazine, isoniazid, penicillamine, and vincristine. Vitamin B6 is also used for nausea and vomiting associated with gastrointestinal illness in children and with use of birth control taken by mouth. Vitamin B6 is frequently used in combination with other B vitamins in vitamin B complex products.
Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
The Effectiveness ratings for Vitamin B6 are as follows:
Likely Effective for...
Possibly Effective for...
Possibly Ineffective for...
Likely Ineffective for...
Insufficient Evidence to Rate Effectiveness for...
More evidence is needed to rate vitamin B6 for these uses.
Vitamin B6 is required for the proper function of sugars, fats, and proteins in the body. It is also required for the proper growth and development of the brain, nerves, skin, and many other parts of the body.
Vitamin B6 is LIKELY SAFE for most people when used appropriately.
Vitamin B6 is POSSIBLY SAFE when taken by mouth in amounts greater than the recommended dietary allowance. In some people, vitamin B6 might cause nausea, vomiting, diarrhea, stomach pain, loss of appetite, headache, tingling, sleepiness, and other side effects.
Long-term use of high doses of vitamin B6 and when vitamin B6 is given as a shot into the muscle is POSSIBLY UNSAFE. When used orally in high doses it might cause certain brain and nerve problems. When given as a shot into the muscle it might cause muscle problems.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Vitamin B6 is LIKELY SAFE for pregnant women when taken under the supervision of their healthcare provider. It is sometimes used in pregnancy to control morning sickness. High doses are UNSAFE. High doses can cause newborns to have seizures.
Vitamin B6 is LIKELY SAFE for breast-feeding women when used in amounts not larger than 2 mg per day (the recommended dietary allowance). Avoid using higher amounts. Not enough is known about the safety of vitamin B6 at higher doses in breast-feeding women.
Procedures to widen narrowed arteries (angioplasty). Using vitamin B6 along with folic acid and vitamin B12 intravenously (by IV) or by mouth might worsen narrowed arteries. Vitamin B6 should not be used by people recovering from this procedure.
Weight loss surgery. Taking a vitamin B6 supplement is not needed for people that have had weight loss surgery. And taking too much vitamin B6 might increase the chance of side effects such as nausea, vomiting, and browning skin.
Diabetes. Using vitamin B6, folic acid, and vitamin B12 might increase the risk of cancer in people with diabetes and a recent stroke. Vitamin B6 should not be used by patients with diabetes that have had a recent stroke.
Interaction Rating = Moderate Be cautious with this combination.
Talk with your health provider.
Amiodarone (Cordarone) might increase your sensitivity to sunlight. Taking vitamin B6 along with amiodarone (Cordarone) might increase the chances of sunburn, blistering, or rashes on areas of skin exposed to sunlight. Be sure to wear sunblock and protective clothing when spending time in the sun.
Interaction Rating = Minor Be watchful with this combination.
Talk with your health provider.
The body breaks down levodopa to get rid of it. Vitamin B6 can increase how quickly the body breaks down and gets rid of levodopa. However, this is only a problem if you are taking levodopa alone. Most people take levodopa along with carbidopa (Sinemet). Carbidopa prevents this interaction from occurring. If you are taking levodopa without carbidopa, do not take vitamin B6.
might lower blood pressure. It has the potential to add to blood pressure-lowering effects of antihypertensive drugs and increase the risk of blood pressure becoming too low.
Some medications used to lower blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
The body breaks down phenobarbital (Luminal) to get rid of it. might increase how quickly the body breaks down phenobarbital (Luminal). This could decrease the effectiveness of phenobarbital (Luminal).
Interaction Rating = Major Do not take this combination.
The body breaks down phenytoin (Dilantin) to get rid of it. vitamin B6 might increase how quickly the body breaks down phenytoin. Taking vitamin B6 and taking phenytoin (Dilantin) might decrease the effectiveness of phenytoin (Dilantin) and increase the possibility of seizures. Do not take large doses of vitamin B6 if you are taking phenytoin (Dilantin).
Vitamin B6 might lower blood pressure. Using vitamin B6 along with other herbs and supplements that can lower blood pressure might cause blood pressure to become too low. Some of these herbs include andrographis, casein peptides, cat's claw, coenzyme Q-10, fish oil, L-arginine, lycium, stinging nettle, theanine, and others.
There are no known interactions with foods.
The following doses have been studied in scientific research:ADULTSBY MOUTH:
INJECTED INTO THE MUSCLE:
INJECTED INTO THE VEIN OR MUSCLE:
The daily recommended dietary allowances (RDAs) of vitamin B6 are: Infants 0-6 months, 0.1 mg; Infants 7-12 months, 0.3 mg; Children 1-3 years, 0.5 mg; Children 4-8 years, 0.6 mg; Children 9-13 years, 1 mg; Males 14-50 years, 1.3 mg; Males over 50 years, 1.7 mg; Females 14-18 years, 1.2 mg; Females 19-50 years, 1.3 mg; Females over 50 years, 1.5 mg; Pregnant women, 1.9 mg; and breast-feeding women, 2 mg. Some researchers think the RDA for women 19-50 years should be increased to 1.5-1.7 mg per day. The recommended maximum daily intake is: Children 1-3 years, 30 mg; Children 4-8 years, 40 mg; Children 9-13 years, 60 mg; Adults, pregnant and breast-feeding women, 14-18 years, 80 mg; and Adults, pregnant and breast-feeding women, over 18 years, 100 mg.
Adermine Chlorhydrate, Adermine Hydrochloride, B Complex Vitamin, B6, Chlorhydrate de pyridoxine, Complexe de Vitamines B, Phosphate de Pyridoxal, Piridoxina, Pyridoxal, Pyridoxal Phosphate, Pyridoxal 5 Phosphate, Pyridoxal-5-Phosphate, Pyridoxamine, Pyridoxine HCl, Pyridoxine Hydrochloride, Pyridoxine-5-Phosphate, P5P, P-5-P, Vitamin B-6, Vitamina B6, Vitamine B6.
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