This summary table contains detailed information about research studies. Summary tables are a useful way to look at the science behind many breast cancer guidelines and recommendations. However, to get the most out of the tables, it’s important to understand some key concepts. Learn how to read a research table.
Introduction: For women who have the option, lumpectomy (also called breast conserving surgery) plus radiation therapy is as effective as mastectomy for treating early breast cancer.
Studies show no difference in overall survival between women treated with either method.
Learn about the strengths and weaknesses of different types of studies.
Study selection criteria: Randomized clinical trials with at least 150 participants and at least 10 years of follow-up, pooled analyses and meta-analyses.
Study Population(number of participants)
Stage ofBreast Cancer*
Overall Survival(for length of follow-up)
Lumpectomyplus Radiation Therapy
Randomized clinical trials
NSABP B-06 
Danish Breast Cancer Cooperative Group 
Veronesi et al. 
National Cancer Institute 
Arriagada et al. 
Pooled and meta-analyses
Jatoi et al. 
van der Hage et al. 
NS = No statistically significant difference between the 2 groups
* Breast cancer stage as classified before 2018
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