Most people diagnosed with breast cancer will never have a breast cancer recurrence (return of breast cancer). However, everyone who has had breast cancer is at risk of recurrence.
Talk with your health care provider about your risk of breast cancer recurrence and things that may lower your risk.
Risk of recurrence varies greatly from person to person and depends on:
If you are diagnosed with a recurrence, it’s not your fault. You did nothing to cause the recurrence.
One major decision you may face with early breast cancer is whether to have a lumpectomy (also called breast conserving surgery) plus radiation therapy or a mastectomy. They are equally effective in treating early breast cancer.
Overall survival is the same for lumpectomy plus radiation therapy versus mastectomy. This means both treatments lower the risk of dying (from breast cancer or other cause) by the same amount.
For a summary of research studies on lumpectomy plus radiation therapy versus mastectomy in the treatment of early breast cancer, visit the Breast Cancer Research Studies section.
The choice between lumpectomy plus radiation therapy versus mastectomy will not affect your survival.
However, it may affect your risk of breast cancer recurrence (the return of cancer) within the breast.
Local recurrence is the return of cancer to the breast, chest wall or lymph nodes after treatment.
Most local recurrences occur within the first 5 years after diagnosis [130-131].
If you have a recurrence, you will need more treatment.
Learn about treatment for local recurrence.
Distant recurrence (metastasis) occurs when cancer spreads beyond the breast and nearby lymph nodes to other organs such as the bones, liver, lungs or brain.
The risk of distant recurrence is the same for people who have lumpectomy plus radiation therapy and those who have mastectomy .
Learn about treatment for distant recurrence (metastatic or advanced breast cancer).
For women who have lumpectomy plus radiation therapy, the chance of local recurrence in 10 years is about 3-15 percent [133-134].
The risk of local recurrence depends on tumor characteristics such as hormone receptor status and HER2 status.
It also depends on whether or not the tumor margins and the lymph nodes in the underarm area contain cancer cells. The chance of local recurrence is lower when [2,132]:
Chemotherapy, hormone therapy and/or targeted therapy can lower the risk of breast cancer recurrence after lumpectomy plus radiation therapy .
With mastectomy, the best predictor of local recurrence is whether the lymph nodes in the underarm area (axillary lymph nodes) contain cancer.
The more axillary lymph nodes with cancer, the higher the risk of recurrence tends to be .
When the axillary nodes don't contain cancer, the chance of local recurrence in 5 years is about 6 percent .
When there is cancer in the axillary nodes, the chance of local recurrence in 5 years is about 23 percent following mastectomy without radiation therapy . Radiation therapy can reduce this risk to about 6 percent .
Learn more about breast cancer recurrence.
Making Treatment Decisions
After Early Breast Cancer: Signs and Symptoms of Metastatic Breast Cancer (MBC)
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