How Hormones Affect Breast CancerPDF, 124KB
The use of menopausal hormone therapy (MHT) increases the risk of both developing and dying from breast cancer (learn more) [103-105]. MHT is also known as postmenopausal hormone use or hormone replacement therapy.
Although MHT is approved for the short-term relief of menopausal symptoms, the U.S. Food and Drug Administration (FDA) recommends women use only the lowest dose that eases symptoms for the shortest time needed .
Learn more about menopausal hormone therapy and breast cancer risk.
Learn more about menopausal hormone therapy and other health risks.
For a summary of research studies on menopausal hormone therapy and breast cancer risk, visit the Breast Cancer Research section.
For breast cancer survivors, avoiding MHT may be more important than for other women. Survivors have an increased risk of getting a second breast cancer and MHT use increases the risk of breast cancer [103-105].
Whether MHT increases the risk of breast cancer recurrence in survivors is still under study. Much of the research done to date has not found a link between the two [107-109]. However, one randomized clinical trial was stopped because the survivors who were taking MHT had more recurrences, metastases and second breast cancers than survivors not taking MHT .
Currently, the best choice for most breast cancer survivors is to avoid the use of MHT. Women should discuss other ways to relieve menopausal symptoms with their health care provider.
Learn about alternatives to menopausal hormone therapy for the relief of menopausal symptoms.
For a summary of research studies on menopausal hormone therapy and breast cancer recurrence, visit the Breast Cancer Research section.
Read our perspective on managing menopausal symptoms (April 2012).
There is no medical or scientific definition for the term “bio-identical hormones,” so you may hear this term used in different ways. Some people use it to describe hormone drugs that have the same chemical and molecular structure as hormones found in the body. (Not all products that claim to be bio-identical meet this definition.) “Bio-identical" may also refer to hormone therapies that are custom compounded (when a pharmacist makes a mixture of hormones according to the physician’s instructions on a prescription) [111-113]. No matter the definition, it is important to remember:
To learn more about bio-identical hormone therapies, visit the FDA website.
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