European mistletoe is a plant that grows on several different trees. The berries, leaf, and stem of European mistletoe are used to make medicine.
Interest in mistletoe for cancer has grown in North America, ever since Suzanne Somers announced on Larry King Live that she is using it to treat her breast cancer. European mistletoe has been used for treating cancer since the 1920s, especially in Europe. Several brand name mistletoe extracts are available there: Iscador, Eurixor, Helixor, Isorel, Vysorel, and ABNOBAviscum. So far these products are not readily available in North America. There is no proof they work for breast or other cancers. Avoid these products and stick with proven cancer treatments.
European mistletoe is also used for heart and blood vessel conditions including high blood pressure, "hardening of the arteries" (atherosclerosis), internal bleeding, and hemorrhoids; epilepsy and infantile convulsions; gout; psychiatric conditions such as depression and anxiety; sleep disorders; headache; absence of menstrual periods; symptoms of menopause; and for "blood purifying."
Some people use European mistletoe for treating mental and physical exhaustion; to reduce side effects of chemotherapy and radiation therapy; as a tranquilizer; and for treating whooping cough, asthma, dizziness, diarrhea, chorea, and liver and gallbladder conditions.
European mistletoe injections are used for cancer and for failing joints.
Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
The effectiveness ratings for European Mistletoe are as follows:
More evidence is needed to rate the effectiveness of European mistletoe for these uses.
European mistletoe has several active chemicals. It might stimulate the immune system and kill certain cancer cells in a test tube, but it doesn't seem to work in people.
European mistletoe is POSSIBLY SAFE when used by mouth or when injected beneath the skin in appropriate amounts. Taking three berries or two leaves or less by mouth does not seem to cause serious side effects. However, larger amounts are LIKELY UNSAFE and cause serious side effects. European mistletoe can cause vomiting, diarrhea, cramping, and other side effects. Short-term, frequent use of European mistletoe might cause liver damage.
Injecting European mistletoe beneath the skin or into the vein can cause fever, chills, skin rashes, pain, allergic reactions, and other side effects.
Because the correct amount is sometimes hard to determine, do not take European mistletoe without the advice of your healthcare professional.
Pregnancy and breast-feeding European mistletoe is LIKELY UNSAFE when taken by mouth or inject under the skin during pregnancy. It might stimulate the uterus and cause a miscarriage.
There is not enough reliable information about the safety of taking European mistletoe if you are breast-feeding. Stay on the safe side and avoid use.
"Auto-immune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: European mistletoe might cause the immune system to become more active, and this could increase the symptoms of auto-immune diseases. If you have one of these conditions, it's best to avoid using European mistletoe.
Heart disease: There is some evidence European mistletoe might make heart disease worse. Don't use it if you have a heart problem.
Leukemia: Some test tube studies suggested European mistletoe might be effective against childhood leukemia. But benefits have not been shown in people. In fact, European mistletoe might make leukemia worse. If you have leukemia, don't take European mistletoe.
Liver disease: There is some concern that taking European mistletoe might harm the liver. In theory, European mistletoe might make liver diseases, such as hepatitis, worse. People with liver disease or a history of liver disease should avoid European mistletoe.
Organ transplant: European mistletoe might make the immune system more active. This would be a problem for people who have received an organ transplant. A more active immune system might increase the risk of organ rejection. If you have had an organ transplant, avoid European mistletoe.
Surgery: European mistletoe might affect blood pressure. There is a concern that it might interfere with blood pressure control during and after surgery. Stop taking European mistletoe at least 2 weeks before a scheduled surgery.
Interaction Rating = Moderate Be cautious with this combination.
Talk with your health provider.
European mistletoe seems to decrease blood pressure. Taking European mistletoe along with medications for high blood pressure might cause your blood pressure to go too low.
Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
European mistletoe might harm the liver. In theory, taking European mistletoe along with medication that might also harm the liver can increase the risk of liver damage.
Some medications that can harm the liver include acarbose (Precose, Prandase), amiodarone (Cordarone), atorvastatin (Lipitor), azathioprine (Imuran), carbamazepine (Tegretol), cerivastatin (Baycol), diclofenac (Voltaren), felbamate (Felbatol), fenofibrate (Tricor), fluvastatin (Lescol), gemfibrozil (Lopid), isoniazid, itraconazole, (Sporanox), ketoconazole (Nizoral), leflunomide (Arava), lovastatin (Mevacor), methotrexate (Rheumatrex), nevirapine (Viramune), niacin, nitrofurantoin (Macrodantin), pioglitazone (Actos), pravastatin (Pravachol), pyrazinamide, rifampin (Rifadin), ritonavir (Norvir), rosiglitazone (Avandia), simvastatin (Zocor), tacrine (Cognex), tamoxifen, terbinafine (Lamisil), valproic acid, and zileuton (Zyflo).
European mistletoe seems to increase the activity of the immune system. By increasing the immune system, European mistletoe might decrease the effectiveness of medications that decrease the immune system.
Some medications that decrease the activity of the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.
There is some evidence that European mistletoe might counteract any positive effects hawthorn might have on heart health.
There is some concern that European mistletoe might harm the liver. In theory, using European mistletoe along with other products that might harm the liver could increase the risk of dangerous liver damage. Some of these products include androstenedione, chaparral, comfrey, DHEA, germander, niacin, pennyroyal oil, red yeast, and others.
European mistletoe might lower blood pressure. Using it along with other herbs or supplements that have this same effect might lower blood pressure too much. Some of these herbs and supplements include andrographis, casein peptides, cat's claw, coenzyme Q-10, fish oil, L-arginine, lycium, stinging nettle, theanine, and others.
There are no known interactions with foods.
All-Heal, Banda, Birdlime Mistletoe, Blandeau, Bois de Sainte-Croix, Bouchon, Devil's Fuge, Drudenfuss, Eurixor, Guérit-Tout, Gui, Gui Blanc, Gui Blanc d'Europe, Gui des Feuillus, Gui d'Europe, Gui Européen, Helixor, Herbe de Chèvre, Hexenbesen, Hurchu, Iscador, Isorel, Leimmistel, Mistlekraut, Mistletein, Mistletoe, Muérdago Europeo, Mystyldene, Nid de Sorcière, Pain de Biques, Rini, Verquet, Vert-Bois, Vert de Pommier, Visci, Visci Albi Folia, Visci Albi Fructus, Visci Albi Herba, Visci Albi Stipites, Vogelmistel, Vysorel, Viscum album.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.
For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.
© Copyright 1995-2018 Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber's Letter, and Pharmacist's Letter. All rights reserved.
Discover the different ways you can help
1-877 GO KOMEN(1-877-465-6636)
Give hope to others in your situation