This summary table contains detailed information about research studies. Summary tables offer an informative look at the science behind many breast cancer guidelines and recommendations. However, they should be viewed with some caution. In order to read and interpret research tables successfully, it is important to understand some key concepts. Learn how to read a research table.
Introduction: Inflammatory breast cancer is a rare, but aggressive form of breast cancer. It is treated with a combination of surgery, radiation therapy and chemotherapy, and may include hormone therapy and/or targeted therapy. This is often called combined modality treatment because multiple therapies are used.
With combined modality treatment, five-year overall survival rates for inflammatory breast cancer range from about 30 to 70 percent (see studies below). With modern treatments available today, survival for women with inflammatory breast cancer appears to be improving. One study found three-year overall survival was 63 percent for women diagnosed before 2006 and 82 percent for women diagnosed after 2006 .
Study selection criteria: Clinical trials with 50 or more participants on combined modality treatment with at least five years follow-up.
Study Population (number of participants)
5-year Overall Survival Rate
Palangie et al. 
Chemotherapy>>radiation therapy>>chemotherapy with or without immunotherapy with or without hormone therapy with or without mastectomy
Ueno et al. 
Chevallier et al. 
Chemotherapy>>radiation therapy with or without mastectomy with or without chemotherapy
Attia-Sobol et al. 
Chemotherapy with or without radiation therapy with or without surgery with or without radiation therapy>>chemotherapy
Untch et al. 
Dose-dense or standard chemotherapy>>lumpectomy>>chemotherapy>>radiation therapy
Dose-dense or standard chemotherapy>>mastectomy with or without radiation therapy>>chemotherapy
Perez et al. 
Harris et al. 
Chemotherapy>>radiation therapy with or without mastectomy>>chemotherapy
* Estimate from figure in article
† Breast cancer survival rather than overall survival
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