• Above all, we make a difference.
  • Return of Breast Cancer after Treatment (Recurrence)

    If Breast Cancer Returns
    Fact Sheet


    Breast Cancer 101 (Interactive Multimedia)  - Survivorship and Recurrence
    Macromedia Flash

    The goal of treating early stage and locally advanced breast cancer is to remove the cancer and keep it from coming back (called recurrence or relapse).

    How is a recurrence or metastasis found?

    Breast cancer can recur at the original site (called recurrence or local recurrence), as well as return and spread to other parts of the body (called metastasis or distant recurrence).

    • Local recurrence is usually found on a mammogram or during a physical exam, either by a health care provider or by yourself.
    • Metastasis is usually found when symptoms are reported during follow-up office visits with your provider.

    Learn about follow-up care after breast cancer treatment.

    Local recurrence

    When a local recurrence is found, it is treated in much the same way as the first breast cancer. The tumor is removed by the surgeon, examined by the pathologist and tested for hormone receptor status, HER2 status and other characteristics. Tests are also done to be sure there is no sign of metastasis.

    Local recurrence after lumpectomy

    Local recurrence after lumpectomy (breast conserving surgery) most often can be treated successfully. Treatment generally includes surgery, usually a mastectomy. Radiation therapy may be given if it was not part of the initial breast cancer treatment. Treatment may also include chemotherapy, hormone therapy and/or targeted therapy.

    Local recurrence after mastectomy

    Even though the entire breast is removed in a mastectomy, breast cancer can still return to the chest area. The more lymph nodes that contained cancer at the time of the mastectomy, the higher the chances of breast cancer recurrence.

    Local recurrence after a mastectomy is usually treated with surgery followed by radiation therapy (if radiation therapy was not part of initial treatment). Treatment may also include chemotherapy, hormone therapy and/or targeted therapy.


    Metastasis (distant recurrence) is most often found when people report symptoms. These may include:

    • Shortness of breath
    • Weight loss
    • Bone pain

    Do not panic if you have symptoms like weight change or bone pain. These are common and most often do not mean that the breast cancer has spread. However, you should discuss any symptoms with your health care provider.

    Based on the symptoms above, tests are done to see if the breast cancer has returned and spread to other organs (metastasized). Depending on the symptoms, follow-up tests, such as blood tests (including tumor marker tests) and imaging tests (including bone scans, CT scans, PET scans and chest X-rays) may be used to check for metastases. Other tests may also be done.

    For people with no symptoms of metastases, blood and imaging tests (other than mammography) are not a standard part of follow-up care. Using blood or imaging tests to check for early metastases in people with no symptoms of metastases does not increase survival [126].

    Breast cancer most often spreads to the bones, lungs, liver or brain. Although it has spread to another part of the body, it is still considered and treated as breast cancer. For example, breast cancer that has spread to the bones is still breast cancer (not bone cancer) and is treated with breast cancer drugs, rather than treatments for a cancer that began in the bones.

    When metastases are present, tests are done to determine which organs are involved and the hormone receptor status and HER2 status of the tumor. Then, you and your provider can discuss treatment options.

    Learn more about treatment of metastatic breast cancer.

    Metastasis and pain management

    Metastatic breast cancer can cause pain in the areas where the cancer has spread. It is important to control any pain related to metastatic breast cancer. Even mild pain can interfere with daily life and make other side effects, such as fatigue, seem worse.

    Learn more about management of pain related to metastatic breast cancer.

    Recurrence and support

    Treatment for breast cancer can be a trying and draining process. If the cancer returns, you may have a strong emotional and physical reaction. A breast cancer support group, especially one focused on breast cancer recurrence, may help you address these concerns.

    Learn more about support groups

    Komen Support Resources

    • Calls to our breast care helpline 1-877 GO KOMEN (1-877-465-6636) are answered by a trained and caring staff member Monday through Friday from 9:00 a.m. to 10:00 p.m. ET and from 6:00 a.m. to 7:00 p.m. PT. Our helpline provides free, professional support services to anyone with breast cancer questions or concerns, including breast cancer survivors and their families. You can also email the breast care helpline at helpline@komen.org
    • Our Message Boards offer online forums for breast cancer survivors to share their experiences and advice with other breast cancer survivors.  

    Updated 07/28/15

    previous Clinical Trials
     Unique Issues for Young Women with
    Breast Cancer

Tools & Resources


Related Video



1-877 GO KOMEN