Natural Standard Monograph, Copyright © 2014 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified health care professional before making decisions about therapies and/or health conditions.
Uses based on scientific evidence
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare professional.
Early research suggests that resveratrol applied to the skin may benefit people who have acne. More studies are needed before conclusions can be made.
There is some evidence suggesting that compounds that contain resveratrol, such as red wine or grape powder, may decrease inflammation. Research has been done to better understand the potential anti-inflammatory benefits of resveratrol. However, information is limited, and further research is needed before conclusions can be made.
Chronic obstructive lung disease
Early research suggests that resveratrol may help reduce inflammation associated with chronic obstructive lung disease. Other studies found that a combination product containing resveratrol improved symptoms. Further research is needed.
Early evidence suggests that resveratrol may increase blood flow, but there are mixed results as to whether resveratrol may affect cognitive function. Further research is needed.
Although the topic has not been well studied in humans, early research suggests that resveratrol may increase insulin sensitivity and reduce blood sugar levels in people who have diabetes. More research is needed before conclusions can be made.
Exercise performance enhancement
Preliminary evidence suggests that a mixture including resveratrol may result in decreased heart rate associated with exercise. Further research is required on exercise performance with resveratrol alone.
Early studies examined the use of a combination therapy that included resveratrol for heart disease risk, but the effect of resveratrol alone cannot be determined from these. A patented product (Stilvid®) containing resveratrol-enriched grape extract was found to offer some beneficial effects on heart disease risk factors. In other research, resveratrol improved heart function in healthy, exercising people. More studies are needed.
Resveratrol has been included in many herbal supplements that are meant to increase lifespan and prevent aging. However, reliable human research is lacking, and more high-quality studies are needed to determine the effects of resveratrol alone.
Early research suggests that resveratrol supplementation may enhance the effects of the seasonal flu vaccine. More high-quality studies are needed.
Early research suggests that resveratrol may not affect body mass but may still contribute to weight loss by improving metabolism. More research is needed.
*Key to grades:
A: Strong scientific evidence for this use;B: Good scientific evidence for this use; C: Unclear scientific evidence for this use;D: Fair scientific evidence against this use (it may not work);F: Strong scientific evidence against this use (it likely does not work).
For full grading rationale, click here.
Uses based on tradition or theory
The below uses are based on tradition or scientific theories. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified health care professional
Allergy, Alzheimer's disease, amyloidosis (abnormal protein buildup), antifungal, antimicrobial, antioxidant, antiviral, arthritis, blood thinner, bone density, brain injuries, breathing problems, cancer, cerebral ischemia (reduced blood flow to the brain), cosmetic, degenerative diseases, dementia, epilepsy, Epstein-Barr virus, general health maintenance, hearing loss, H. pylori infection, herpes simplex virus types 1 and 2, HIV, hormonal imbalances, Huntington's disease, increased muscle mass, immune system regulation, infertility, ischemia-reperfusion injury prevention (prevention of tissue damage after restored blood flow), kidney problems, lipid lowering effects, liver protection, macular degeneration (eye disease), menopausal symptoms, metabolic syndrome, multiple sclerosis, nerve disorders, neuropathy (nerve damage), obesity, pain, pancreatitis (inflammation of the pancreas), Parkinson's disease, pulmonary hypertension (high blood pressure in the lungs), seizure, skin care, spinal cord injury, stomach disorders, stroke, swelling, vasorelaxant (lowers blood vessel pressure), wound healing.
The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare professional before starting a new therapy. Consult a healthcare professional immediately if you experience side effects.
Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare professional before starting a new therapy.
Natural Standard developed the above evidence-based information based on a systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
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