Reishi mushroom is a fungus that some people describe as “tough” and “woody” with a bitter taste. The fruiting body (above-ground part) and mycelium (filaments connecting a group of mushrooms) are used as medicine.
Reishi mushroom is used for boosting the immune system; viral infections such as the flu (influenza), swine flu, and avian flu; lung conditions including asthma and bronchitis; heart disease and contributing conditions such as high blood pressure and high cholesterol; kidney disease; cancer; and liver disease. It is also used for HIV/AIDS, altitude sickness, chronic fatigue syndrome (CFS), trouble sleeping (insomnia), stomach ulcers, poisoning, and herpes pain. Other uses include reducing stress and preventing fatigue.
In combination with other herbs, reishi mushroom is used to treat prostate cancer.
Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
The effectiveness ratings for REISHI MUSHROOM are as follows:
More evidence is needed to rate the effectiveness of reishi mushroom for these uses.
Reishi mushroom extract is POSSIBLY SAFE when taken by mouth appropriately for up to one year.
Reishi mushroom is POSSIBLY UNSAFE when taken by mouth in a powdered form for more than one month. Use of powdered reishi mushroom has been associated with toxic effects on the liver.
Reishi mushroom can also cause other side effects including dryness of the mouth, throat, and nasal area along with itchiness, stomach upset, nosebleed, and bloody stools. Drinking reishi wine can cause a rash. Breathing in reishi spores can trigger allergies.
Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking reishi mushroom if you are pregnant or breast feeding. Stay on the safe side and avoid use.
Bleeding disorder: High doses of reishi mushroom might increase the risk of bleeding in some people with certain bleeding disorders.
Low blood pressure: Reishi mushroom seems to be able to lower blood pressure. There is a concern that it might make low blood pressure worse and could interfere with treatment. If your blood pressure is too low, it is best to avoid reishi mushroom.
A clotting disorder called thrombocytopenia: High doses of reishi mushroom might increase the risk of bleeding in people with thrombocytopenia. If you have this condition, do not use reishi mushroom.
Surgery: High doses of reishi mushroom might increase the risk of bleeding in some people if used before or during surgery. Stop using reishi mushroom at least 2 weeks before a scheduled surgery.
Interaction Rating = Moderate Be cautious with this combination.
Talk with your health provider.
Reishi mushroom might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking reishi mushroom along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), and others.
Reishi mushroom might decrease blood pressure in some people. Taking reishi mushroom along with medications for high blood pressure might cause your blood pressure to go too low.
Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others.
High doses of reishi mushroom might slow blood clotting. Taking reishi mushroom along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Reishi mushroom might lower blood pressure. Taking it along with other herbs and supplements that have this same effect might make blood pressure drop too low. Some of these herbs and supplements include andrographis, casein peptides, cat's claw, coenzyme Q-10, fish oil, L-arginine, lycium, stinging nettle, theanine, and others.
Reishi mushroom might lower blood sugar. Using it along with other herbs and supplements that have the same effect might cause blood sugar to drop too low in some people. Some of these products include alpha-lipoic acid, bitter melon, chromium, devil's claw, fenugreek, garlic, guar gum, horse chestnut seed, Panax ginseng, psyllium, Siberian ginseng, and others.
The effect of reishi mushroom on blood clotting is not clear. Higher amounts (about 3 grams per day) but not lower doses (1.5 grams per day) might slow blood clotting. There is a concern that taking reishi mushroom along with other herbs that slow blood clotting could increase the risk of bruising and bleeding. Some of these herbs include angelica, anise, arnica, clove, danshen, garlic, ginger, ginkgo, Panax ginseng, horse chestnut, red clover, turmeric, and others.
Natural Medicines disclaims any
responsibility related to medical consequences of using any medical
product. Effort is made to ensure that the information contained in this
Natural Medicines monograph is accurate at the time it was published.
However, we cannot guarantee the information is error-free and disclaim
any liability or responsibility for any reliance on it. The information
is also not intended to be a substitute for medical or other
professional advice, and you should not use any product or substances
reference herein without consulting a medical professional. Consumers
and medical professionals who consult this Natural Medicines
monograph are cautioned that any medical or product related decision is
the sole responsibility of the consumer and/or the health care
professional. A legal License Agreement sets limitations on downloading,
storing, or printing content from Natural Medicines. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from Natural Medicines is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from Natural Medicines or this site.
For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of Natural Medicines. It is fully referenced and updated daily.
© Copyright 1995-2015 Therapeutic Research Center, publishers of Natural Medicines, Prescriber's Letter, and Pharmacist's Letter. All rights reserved.
Discover the different ways you can help
1-877 GO KOMEN(1-877-465-6636)
Give hope to others in your situation