Natural Standard Monograph, Copyright © 2014 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. You should consult with a qualified health care professional before making decisions about therapies and/or health conditions.
Uses based on scientific evidence
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare professional.
A combination of reishi mushroom and San Miao San (a mixture of several Chinese herbs) may help reduce the pain of rheumatoid arthritis. These herbs lacked an effect on swelling. More research with reishi mushroom alone is needed.
Reishi has been shown to have anti-cancer and immune enhancing effects in nonhuman research. In human research, Ganopoly®, a reishi extract, resulted in improved quality of life and enhanced immune responses in people receiving treatment for advanced cancer. It is important to note that these data were published by authors affiliated with the manufacturer of Ganopoly®. Further research is needed to reach conclusions.
Chronic hepatitis B
Early evidence showed that Ganopoly® treatment decreased the amount of hepatitis B virus (HBV) in the blood. This virus is hard to clear from the body and recurrence after treatment is common. The affiliation of authors to the manufacturer of the drug is noteworthy. Further well-designed research is needed before a strong recommendation can be made.
Diabetes mellitus type 2
Non-human research showed that reishi lowers blood sugar and cholesterol levels. In limited human research, Ganopoly® slightly improved diabetes markers. The authors are closely related to the manufacturer of Ganopoly®. Further research is needed.
In limited human research, Ganopoly® improved symptoms of heart disease such as chest pain, increase heart rate, and shortness of breath. Blood pressure and cholesterol were also decreased. The authors are closely related to the manufacturer of Ganopoly®. Further research is needed to draw conclusions.
Heart disease prevention
In early human research, reishi lacked an effect on blood pressure and cholesterol levels (which increase heart disease risk). Further research is needed.
High blood pressure
Ancient Chinese monks utilized the reishi mushroom to calm their minds for meditation. Early research suggests that reishi may lower blood pressure. Future research is needed to make conclusions.
Early research showed reishi extract to be effective in decreasing postherpetic pain (pain after herpes lesions heal). Further research is needed to confirm these results.
Poisoning (Russula subnigricans)
In early research, reishi has shown a beneficial effect in treating poisoning with Russula subnigricans. Further research is needed to confirm these results.
Proteinuria (protein in the urine)
Early research showed reishi to be effective in decreasing protein in the urine in people with kidney disease. Further research is needed to draw conclusions.
*Key to grades:
A: Strong scientific evidence for this use;B: Good scientific evidence for this use; C: Unclear scientific evidence for this use;D: Fair scientific evidence against this use (it may not work);F: Strong scientific evidence against this use (it likely does not work).
For full grading rationale, click here.
Uses based on tradition or theory
The below uses are based on tradition or scientific theories. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified health care professional
Adaptogen (decrease stress), altitude sickness, anti-aging, anti-inflammatory, antibacterial, antioxidant, antiviral, asthma, blood cleanser, blood thinner, bronchitis, cough, dizziness, fatigue, hormonal disorders, immune system enhancement, insomnia, kidney inflammation, lipid lowering (cholesterol and triglycerides), liver disorders, low white blood cell count, memory, muscular dystrophy (muscle loss and weakness), myasthenia gravis (muscle weakness and fatigue), neurasthenia (chronic weakness and fatigue), nerve disorders, pain (general), poisoning (general), sedative, seizure, tension, ulcers.
The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare professional before starting a new therapy. Consult a healthcare professional immediately if you experience side effects.
Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare professional before starting a new therapy.
Natural Standard developed the above evidence-based information based on a systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to www.naturalstandard.com. Selected references are listed below.
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