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Home > Understanding Breast Cancer > Risk Factors and Prevention > Preventive Surgery


Preventive Surgery


Prophylactic Mastectomy
Fact Sheet

Prophylactic mastectomy

Prophylactic mastectomy and breast cancer risk

Bilateral prophylactic (PRO-fih-LAK-tik) mastectomy is the removal of both breasts to prevent breast cancer. Studies suggest prophylactic bilateral mastectomy can lower the risk of breast cancer in women at high risk by 90 percent or more [245-252].  

Some BRCA1 or BRCA2 carriers and women with a strong family history choose this option because it eases their worries about getting breast cancer. It may also make them feel they have done all they can do to prevent breast cancer.

The pros and cons of prophylactic mastectomy

A woman at high risk for breast cancer should talk with her health care provider about the pros and cons of prophylactic mastectomy. Prophylactic mastectomy does not completely protect a woman from breast cancer [248-252]. A mastectomy is not able to remove all of a woman's breast tissue. This means there is always a small chance breast cancer could occur in the remaining tissue.  

The benefits of prophylactic mastectomy seem to be greatest in younger women. Younger women have more years of life ahead than older women. For a 30-year old woman who has a BRCA1 or BRCA2 gene mutation, the procedure may add three to five years to her lifespan [246,253-254]. For women 60 years and older, the gain in lifespan after a prophylactic mastectomy is small.  

Prophylactic mastectomy has some risks, including problems (such as infection) from surgery. And, in addition to the emotional impact of losing both breasts, some women have body image issues that can affect how they feel sexually [252,282-284]. Talking to a health care provider or counselor, or joining a support group, can help address these issues.  

Learn more about sexuality and intimacy after breast surgery.

Learn more about support groups.

Breast reconstruction after prophylactic mastectomy

If you choose to have a prophylactic mastectomy, you may wish to have breast reconstruction at the same time as the mastectomy or at a later time. Learn more about breast reconstruction.

Insurance coverage

At this time, no federal laws require insurance providers to cover prophylactic mastectomy. Some states do have a law requiring coverage for prophylactic mastectomy, but coverage varies state to state. It is best to check with your insurance provider to learn about your plan’s coverage.    

 Komen Perspectives 

 Read our perspective on prophylactic mastectomy (February 2014).*   


Prophylactic oophorectomy

Women with a BRCA1 or BRCA2 gene mutation are at higher risk of both breast cancer and ovarian cancer. One option for reducing risk is prophylactic oophorectomy (surgical removal of the ovaries). This procedure lowers the risk of [253,255-262,529]:

  • Ovarian cancer by 70 to over 90 percent
  • Breast cancer by 40 to 70 percent

The National Comprehensive Cancer Network (NCCN) recommends women from families with hereditary ovarian cancer syndromes, including BRCA1 and BRCA2 carriers, have oophorectomy between ages 35 and 40 (or after childbearing is complete) [244].

Support for women with hereditary breast and/or ovarian cancer

Some support groups are tailored for BRCA1 and BRCA2 carriers and those with BRCA-related cancers. Our Support section offers a list of resources to help find a local or on-line support group. For example, FORCE and Sharsheret are organizations that have on-line support for women affected by hereditary breast and/or ovarian cancer. Our Helpline1-877 GO KOMEN (1-877-465-6636) can also provide support for BRCA1 and BRCA2 carriers and those considering genetic testing.  


Komen Support Resources  

  • Our breast care helpline 1-877 GO KOMEN (1-877-465-6636) provides free, professional support services and help finding local support groups. Our trained and caring staff are available to you and your family Monday through Friday from 9:00 a.m. to 10:00 p.m. ET and from 6:00 a.m. to 7:00 p.m. PT. 
  • Our Message Boards offer online forums to share your thoughts or feelings about subjects related to breast cancer. Our Women at Higher Risk of Breast Cancer forum within the Message Boards offers women at higher risk a place to share their own unique experiences and challenges.


Updated 04/03/14


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