Family history and some inherited genetic mutations (changes) affect breast cancer risk in both men and women. Having an immediate family member (a parent, sibling or child) with a history of breast cancer increases your own risk of breast cancer. Although rare, mutations in the BRCA1 and BRCA2 genes increase risk of breast and other cancers. Learn more about family history and genetic factors and how they affect breast cancer risk. You can also find information on genetic testing and options for women at higher risk of breast cancer.