DCIS (ductal carcinoma in situ) is a non-invasive breast cancer.
Many issues about how best to treat DCIS are under study, including:
After discussing the benefits and risks with your health care provider, we encourage you to consider joining a clinical trial of a new treatment for DCIS.
BreastCancerTrials.org in collaboration with Susan G. Komen offers a custom matching service that can help you find a clinical trial that fits your health needs.
Learn more about clinical trials.
Radiation therapy after lumpectomy for DCIS decreases the risk of DCIS recurrence and the risk of invasive breast cancer [2-8].
However, overall survival is the same for women with DCIS who have lumpectomy with or without radiation therapy [2,4]. So, there are questions about the need for radiation therapy after lumpectomy for DCIS.
Select women with smaller, lower-grade DCIS and clean surgical margins may be able to have lumpectomy without radiation therapy [2,9]. However, which women might be able to avoid radiation therapy is still under study.
For a summary of research studies on lumpectomy plus radiation therapy as a treatment for DCIS, visit the Breast Cancer Research Studies section.
Oncotype DX is a test that helps predict the chance of metastasis (when cancer spreads to other organs) for some invasive breast cancers. It tests a sample of the tumor (removed during a biopsy or surgery) for a group of 21 genes.
The Oncotype DX test for invasive breast cancer has been modified to help predict the chance that DCIS will return as DCIS or invasive breast cancer . This could help identify which cases of DCIS would benefit most from radiation therapy after lumpectomy (and which women might be treated with lumpectomy alone) .
The Oncotype DX test for DCIS needs further study and is not part of standard practice at this time.
Learn more about Oncotype DX for invasive breast cancer.
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Our commitment to research
Research is one of our best weapons against breast cancer. Over the past 30 years, it’s fueled our knowledge of breast cancer and helped us understand that breast cancer is not just a single disease but many diseases, unique to each individual. Komen’s funding has provided more than $889M to researchers in 49 states and 20 countries to support research that has resulted in a better understanding of breast cancer; earlier detection; personalized, less invasive treatments for what was once a “one-treatment-fits-all” disease; and improved survival rates. Learn more about our continuing investment in research, because nothing would make us happier than ending breast cancer forever.
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*Please note, the information provided within Komen Perspectives articles is only current as of the date of posting. Therefore, some information may be out of date at this time.
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