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    Home > Research & Grants > Grants Program > Research Grants > Research Grants Awarded

    Research Grants Awarded

    2004-2005 Grant Cycle : Research Grants Awarded

    Biology of Breast Cancer

    Role of Cyclin E in the Presence or Absence of CDK2 in Breast Tumorigenesis
    said akli, PhD
    University of Texas M.D. Anderson Cancer Center

    $249,999


    Cell Cycle Checkpoint Functions of the BRCA1/BARD1 Tumor Suppressor Complex
    Richard Baer, PhD
    Columbia University

    $250,000


    Regulation of the Preferential Skeletal Metastasis of Breast Cancers by Runx2
    George Barnes, PhD
    Boston University

    $249,661


    A TGF-beta Responsive Gene Therapy Vector (TRGT) that Specifically Kills Metastatic Breast Cancer
    Stacy Blain, PhD
    SUNY Downstate Medical Center

    $245,857


    The Role of Androgen Receptor Signaling in the Breast: Potential Disruption by Synthetic Progestins Used in Hormone Replacement Therapy
    Lisa Butler, PhD
    University of Adelaide

    $249,999


    Understanding the Tumor Suppression Function of BRCA1
    Junjie Chen, PhD
    Yale University

    $250,000


    The Role of KLF5 Transcription Factor Degradation in Breast Cancer
    Ceshi Chen, PhD
    Albany Medical College

    $249,995


    The Role of Chemokines and Their Receptors in Breast Cancer
    Gina Chung, MD
    Yale University

    $250,000


    Cooperation of Adipocytes with Breast Cancer Cells Promotes an Invasive Phenotype
    Frank Church, PhD
    University of North Carolina at Chapel Hill

    $250,000


    Prolyl Isomerase Function in Breast Cancer
    Charles Clevenger, MD, PhD
    Northwestern University

    $249,999


    Investigating the Role of the NFAT Signaling Pathway in Mammary Tumorigenesis
    Neil Clipstone, BSc, PhD
    Loyola University in Chicago

    $250,000


    Characterizing the Beta-Catenin Transgenic Model of Hormone-Independent Breast Cancer
    PAMELA COWIN, PhD
    New York University School of Medicine

    $250,000


    DNA Repair and the Etiology of Estrogen Receptor Positive Breast Cancer
    David Crowe, PhD
    University of Southern California

    $250,000


    Transcription Profiling of Protein Kinase C Activation in a Panel of Breast Cancer Cells Identifies a Strong Genetic Signature Consistent with Invasion and Metastasis
    Heather Cunliffe, PhD
    Translational Genomics Research Institute

    $250,000


    Does Heat Shock Protein 27 (Hsp27) Play Any Immunomodulatory Role in Breast Cancer?
    Asit De, PhD
    University of Rochester Medical Center

    $249,922


    Endothelin-1 Effects on the Development of Breast Cancer Bone Metastases
    Didier Dreau, PhD
    University of North Carolina at Charlotte

    $218,812


    The Role of Six1, and its Target Cyclin A1, in Breast Cancer
    Heide Ford, PhD
    University of Colorado Health Sciences Center

    $250,000


    Regulation of Prolactin Receptor Stability and Signaling by Ras Oncogene
    Serge Fuchs, MD, PhD
    University of Pennsylvania

    $250,000


    Analysis of O-glycans Involved in Lung Metastasis of Breast Cancer
    Michiko Fukuda, PhD
    The Burnham Institute

    $250,000


    Conditional Loss of the Mitotic Spindle Checkpoint in Chromosomal Instability and Tumorigenesis
    Andrei Goga, MD, PhD
    University of California, San Francisco

    $250,000


    Role of Telomerase and Telomeres in the Tumorigenesis of Breast Cancer
    Jianlin Gong, MD
    Boston University

    $250,000


    Inhibition of Leptin Signaling for Treatment of Breast Cancer
    Ruben-Rene Gonzalez, PhD
    Boston Biomedical Research Institute

    $250,000


    Role of the Breast Cancer Cell 2 (BRCC2) Tumor Suppressor Gene in Early-Onset Breast Cancer
    Bassem Haddad, MD
    Georgetown University

    $250,000


    The FGF Receptor is a Target for N-Cadherin in Breast Cancer Invasion
    Rachel Hazan, PhD
    Albert Einstein College of Medicine of Yeshiva University

    $250,000


    Incidence of DSS1 Mutations in High Risk Breast Cancer Families
    William Holloman, PhD
    Weill Medical College of Cornell University

    $250,000


    Molecular Mechanisms Underlying Aggressive Conversion of Dormant Breast Cancer Metastasis
    Yibin Kang, PhD
    Princeton University

    $250,000


    Characterization of Survivin Contribution to ErbB2-Mediated Drug Resistance
    Irene Kazhdan, MD, PhD
    University of Texas Health Science Center at San Antonio

    $249,856


    Characterization of a Novel Protein Implicated in Breast Cancer Progression
    Kum KUm Khanna, PhD
    The Queensland Institute of Medical Research

    $248,250


    Breast Cancer Stem Cells in the Formation of Bone Metastasis
    Charlotte Kuperwasser, PhD
    Tufts University School of Medicine

    $250,000


    The Roles Of Selenium Compounds In Inhibiting Proliferation And Metastasis Of Breast Cancer
    Andrew Lane, PhD
    University of Louisville

    $250,000


    Transcriptional Gene Interactions in Breast Cancer: Discovery and Analysis of Risk-Associated Regulatory Polymorphisms Combining Microarray and Linkage Analyses
    Garry Larson, PhD
    Beckman Research Institute of the City of Hope

    $249,998


    Genes Providing Resistance to Tamoxifen: Development and Validation of Clinical Biomarkers
    Victor Levenson, MD, PhD
    Northwestern University

    $250,000


    Identification of Estrogen Regulated Metastasis-Associated Genes Involved in Breast Cancer Bone Metastases
    Anait Levenson, MD, PhD
    Northwestern University

    $250,000


    Wip1 As A Novel Therapeutic Target For Human Breast Cancer
    Yong Liao, PhD
    University of Texas M.D. Anderson Cancer Center

    $250,000


    Molecular Imaging of CXCR4 in Breast Cancer: Effects on Tumor Angiogenesis
    Gary Luker, MD
    University of Michigan Medical School

    $250,000


    The Role of Osteoprotegrin-Ligand in Progesterone-Dependent Mammary Morphogenesis and Tumorigenesis
    John Lydon, PhD
    Baylor College of Medicine

    $249,999


    Toward Complete Inhibition of Spontaneous Mammary Tumors by a Combinational HSP110-HER-2/neu Chaperone Vaccine
    Masoud Manjili, VMD, PhD
    Virginia Commonwealth University

    $249,380


    EphA2, a Novel Target for Breast Cancer Therapy
    Kathy Miller, MD
    Indiana University

    $250,000


    Promiscuous Her3 signaling; A New Target in the Treatment of Breast Cancer
    Mark Moasser, MD
    University of California, San Francisco

    $250,000


    Designer Transcription Repressors: Toward the Treatment of Endocrine Resistant Breast Cancers
    Mesut Muyan, DVM, PhD
    University of Rochester

    $249,889


    Reversal of Tumor-Induced Immune Suppression
    Suzanne Ostrand-Rosenberg, PhD
    University of Maryland Baltimore County

    $250,000


    Ginkgo Biloba Extract in the Treatment of Human Breast Cancer
    Vassilios Papadopoulos, PhD
    Georgetown University Medical Center

    $250,000


    Significance of Shc-dependent Signaling Pathways in Breast Cancer Angiogenesis
    Morag Park, PhD
    McGill University

    $249,999


    Invasive Breast Cancer: HBP1 as a Clinical and Molecular Predictor
    Kurtz Paulson, PhD
    Tufts-New England Medical Center

    $250,000


    A Candidate Breast and Ovarian Tumor Suppressor Gene on Chromosome 17p13.3
    Nancy Phillips, MD
    Saint Louis University

    $250,000


    The Role of HSF-1 in the Enhancement of Osteoclastogenesis and Bone Metastasis by the Hsp90 Inhibitor, 17-AAG
    John Price, BSc (Hons), PhD
    Monash University

    $250,000


    Tumor-Stromal Interactions in Breast Cancer Bone Metastasis
    Janet Price, PhD
    University of Texas M.D. Anderson Cancer Center

    $250,000


    MLK3 Meets Pak1 in Breast Cancer: A Prognostic Factor and a Therapeutics Target
    Ajay Rana, PhD
    Texas A & M University Health Science Center

    $250,000


    BRCA1 Regulation of Progesterone Receptor Function in Breast Cancer
    Eliot Rosen, MD, PhD
    Georgetown University

    $250,000


    Molecular Basis of Bone Metastasis in Breast Cancer
    Gary Sahagian, PhD
    Tufts University School of Medicine

    $250,000


    MRJ: A Molecular Switch for Cell Cycle and Cancer Metastasis
    Rajeev Samant, PhD
    University of South Alabama

    $250,000


    Analysis of Proteomic Patterns in Breast Cancer and Associated Tumor Stroma
    Melinda Sanders, M.D.
    Vanderbilt University School of Medicine

    $249,999


    Novel Imaging Techniques to Compare Estrogen Receptor Structure in Tumors and Normal Tissues of Intact Living Animals
    Fred Schaufele, PhD
    University of California, San Francisco

    $250,000


    Prevention of Breast Cancer by Sphingolipids: Importance of EGFR Regulation
    Eva Schmelz, PhD
    Wayne State University

    $250,000


    Cross-Talk Between ER Coregulators and Growth Factor Pathways in Breast Cancer Endocrine Resistance
    Dipali Sharma, PhD
    Emory University

    $249,618


    Roles of BIK Apoptosis-inducing Protein in Breast Cancer
    Toshihiro Shioda, MD, PhD
    Massachusetts General Hospital

    $249,565


    STAT5 as a Common Mediator of Estrogen and Growth Factor Signaling in Breast Cancer
    Corinne Silva, PhD
    University of Virginia

    $249,814


    The Cul3 Ubiquitin Ligase Is A Potential Marker for Breast Epithelial Tumorigenesis
    Jeffrey Singer, BS, MS, PhD
    Brown University

    $250,000


    Targeting Indoleamine 2,3-Dioxygenase to Block Breast Cancer Metastasis
    Todd Skaar, PhD
    Indiana University

    $250,000


    The Stroma as a Gatekeeper of Tumor Development
    Ana Soto, MD
    Tufts University

    $250,000


    Significance of Histone Deacetylase Inhibitors in Breast Cancer
    Rakesh Srivastava, PhD
    Univ. of Texas Health Center at Tyler

    $250,000


    Stat5 a Novel Therapeutic Protein for Breast Cancer Invasion and Mesenchymal Transition Regulation
    Ahmed Sultan, MMS, PhD
    Georgetown University

    $250,000


    Role of BRCA2 in Homology-Directed Repair of DNA Breaks
    Patrick Sung, Dphil
    Yale University

    $250,000


    Role of Coagulant Proteases in Breast Cancer Cell Invasion
    JoAnn Trejo, PhD
    University of North Carolina at Chapel Hill

    $250,000


    Value of molecular markers in predicting long-term outcome in ductal carcinoma in situ of the breast.
    Christopher Umbricht, MD, PhD
    Johns Hopkins University

    $250,000


    Phenotypic and Genomic Alterations in Epithelial Atypia and In Situ Breast Neoplasia
    Frederic Waldman, MD, PhD
    University of California, San Francisco

    $249,967


    Novel Targeting of TGFb in Osteolytic Metastasis
    Mark Waltham, PhD
    St. Vincent's Institute of Medical Research

    $250,000


    Cyclin D1 Regulation of Nuclear Receptor Function
    Chenguang Wang, PhD
    Georgetown University

    $250,000


    Directed Kinome Resequencing to Define New Targeted Therapies for “Basal-Like” Breast Cancer
    Mark Watson, MD, PhD
    Washington University

    $249,554


    Defining the Oncogenic Role of NPM/B23 Through Ribosome Biology
    Jason Weber, PhD
    Washington University

    $249,209


    Role of the BRCA1-FANCD2 Pathway in the Repair of DNA Double-Strand Breaks by Non-Homologous Recombination
    Henning Willers, MD
    Massachusetts General Hospital

    $249,602


    TWEAK: A New Molecular Target for Breast Cancer Therapy?
    Jeffrey Winkles, PhD
    University of Maryland School of Medicine

    $249,929


    Development of Glycosylation-based Therapies for Breast Cancer: Targeting Sialic Acid-Mediated Metastasis with Metabolic Analogs that Modulate Sialoside Biosynthesis
    Kevin Yarema, BS & PhD
    The Johns Hopkins University

    $250,000


    Cancer Control, Survivorship and Outcomes Research

    Improving Informed Consent: A Randomised Controlled Trial of a Decision Aid for Women Invited to Participate in a Breast Cancer Prevention Trial (IBIS-2)
    Phyllis Butow, PhD
    University of Sydney

    $244,000


    Linking Lymphedema to Disorders of Lymphangiogenesis
    Mary Kosir, MD
    Wayne State University

    $250,000


    Breast Cancer Prevention: Methods of Risk Communication
    Elissa Ozanne, PhD
    Massachusetts General Hospital

    $250,000


    Yoga of Awareness Program for Menopausal Symptoms in Women at High Risk for Breast Cancer
    Laura Porter, PhD
    Duke University

    $250,000


    Feasibility of Physical Activity and Relaxation Training for Cancer Survivors
    Carolyn Rabin, PhD
    Miriam Hospital

    $242,334


    Early Detections, Diagnosis, and Prognosis

    Identification and Differentiation of Breast Masses by a Novel Imaging Method
    Azra Alizad, MD
    Mayo Clinic College of Medicine

    $250,000


    Metabolic Imaging of Breast Cancer Glycosylation
    Carolyn Bertozzi, BS, PhD
    University of California, Berkeley

    $249,999


    Contrast-Enhanced Dual Energy Mammography
    John Boone, PhD
    University of California, Davis

    $250,000


    A New MRI Dextran-Based Contrast Agent for Early Detection and Diagnosis of Breast Cancer
    Yuko Kono, MD, PhD
    University of California, San Diego

    $249,920


    Spiegelmers as Inhibitors and Targeting Vehicles Against ErbB Receptors
    Ralf Landgraf, PhD
    University of California, Los Angeles

    $249,936


    Identification and Validation of Biomarkers for Breast Cancer in Nipple Aspiration Fluid
    Jinong Li, PhD
    Johns Hopkins University

    $249,761


    Imaging Breast Cancer Markers with Nanoparticle Enhanced Ultrasound
    Jun Liu, PhD
    The Ohio State University

    $249,604


    Tc-99m Labeled Multivalent RGD peptide for Breast Cancer Imaging
    Shuang Liu, PhD
    Purdue University

    $243,973


    Positron Emission Mammography Camera with Avalanche Gain
    Alla Reznik, PhD
    Sunnybrook and Women’s College Health Sciences Centre

    $250,000


    Molecular Breast Imaging: Evaluation of a New Technique Using Scintimammography as a Potential Screening Tool for Women at Increased Risk of Breast Cancer
    Deborah Rhodes, MD
    Mayo Clinic Rochester

    $249,900


    Protein Signatures of Microinvasive (ER-) and Adjacent Noninvasive (ER+) Cell Clusters During the Progression of In Situ Lesions to Invasive Carcinomas
    Qing-Xiang Sang, PhD
    Florida State University

    $249,946


    F18-PET Detection of Breast Cancer Micrometastasis by CXCR4 Antagonist
    Hyunsuk Shim, PhD
    Emory University

    $250,000


    Protein Microarrays for the Detection of Breast Cancer
    Michael Tainsky, PhD
    Wayne State University

    $250,000


    Mechanism of Protein Kinase C Alpha-Mediated Tamoxifen-Resistant Breast Cancer
    Debra Tonetti, PhD
    University of Illinois

    $249,912


    A Novel Approach to Monitor Genetic Changes Associated with Breast Cancer Progression
    Jonathan Uhr, MD
    University of Texas Southwestern Medical Center at Dallas

    $248,385


    New PET Reporter Probes for Imaging HSV-tk Gene Expression in Breast Cancer
    Qi-Huang Zheng, PhD
    Indiana University

    $250,000


    Etiology

    A Prospective Study of Alcohol Intake, Genetic Susceptibility and Breast Cancer Overall Health Risk
    Rosa Crum, MD, MHS
    Johns Hopkins University Bloomberg School of Public Health

    $249,632


    A Comprehensive Genomic Approach to Characterize the Role of Genetic Variation in IGF Receptor Genes in Relation to Breast Cancer Risk: The Multiethnic Cohort
    Christopher Haiman, ScD
    University of Southern California

    $250,000


    LRBA: A Target for More Effective Breast Cancer Treatments
    William Kerr, PhD
    H. Lee Moffitt Cancer Center and Research Institute

    $249,999


    Prevention

    A Novel MUC1 Targeted Vaccine for the Treatment of Breast Cancer
    Virginia Borges, MD
    University of Colorado Health Science Center

    $240,335


    Sensitizing ER-Negative Breast Cancer Cells to Tamoxifen-Induced Apoptosis by a Novel PDK-1 Inhibitor
    Ching-Shih Chen, PhD
    Ohio State University

    $250,000


    A New Animal Model for Breast Cancer Development in Obese Post-Menopausal Women: Mechanism and Role of Diet
    Reza Hakkak, PhD
    Arkansas Children's Hospital Research Institute

    $250,000


    Activation of FOXO Tumor Suppressor for Breast Cancer Therapy and Prevention
    Mickey Hu, PhD
    University of Texas M.D. Anderson Cancer Center

    $250,000


    Artemisinin and Artemisinin-Tagged Transferrin for Prevention and Treatment of Breast Cancer
    Henry Lai, PhD
    University of Washington

    $249,663


    Mechanisms of Mult-Drug Resistance in Breast Cancer Chemotherapy
    Judy Raucy, BS, MS, PhD
    California Toxicology Research Institute

    $250,000


    INK4/ARF in Parity-Induced Protection of Breast Cancer
    Thenaa Said, PhD
    Baylor College of Medicine

    $250,000


    Scientific Model Systems

    Imaging the Molecular Mechanisms of DNA Damage Repair
    Eric Greene, PhD
    Columbia University

    $250,000


    Role of Separase in Breast Cancer
    Debananda Pati, PhD
    Baylor College of Medicine

    $250,000


    Treatment

    Devlopment of Breast Cancer Targeting Gene Therapy Vectors
    Michael Barry, PhD
    Baylor College of Medicine

    $249,790


    A Pilot Study of Intraoperative Margin Assessment Comparing Optical Spectroscopy and Frozen Section Analysis for Ductal Carcinoma In-Situ of the Breast
    Tara Breslin, MD
    University of Wisconsin System

    $84,242


    Pre-Clinical Evaluation of Novel Hsp90 Inhibitors in Breast Cancer
    Gabriela Chiosis, PhD
    Memorial Sloan-Kettering Cancer Center

    $250,000


    Using HIF-1 Blockade to Improve Chemotherapy Efficacy in Human Breast Cancer
    Mark Dewhirst, DVM, PhD
    Duke University

    $249,998


    A Novel Vascular Targeting Antibody, 3G4, Enhances the Therapeutic Efficacy of Docetaxel Against Drug Resistant Breast Cancer and Metastases
    Xianming Huang, PhD
    UT Southwestern Medical Center at Dallas

    $247,318


    Targeting the Cell Cycle in Breast Cancer Treatment
    Kelly Hunt, MD
    University of Texas M.D. Anderson Cancer Center

    $249,819


    Characterization of Breast Motion and its Dosimetric Consequences
    Robert Jeraj, PhD
    University of Wisconsin, Madison

    $250,000


    P450-armed Replication-Specific/Adaptive Adenovirus for Chemo-resistant Breast Cancer Treatment
    Youssef Jounaidi, PhD
    Boston University

    $249,867


    Targeting PPARgamma by CDDO: A Novel Therapy for Resistant Breast Cancer
    Marina Konopleva, MD, PhD
    University of Texas M.D. Anderson Cancer Center

    $250,000


    Her2-Targeted Adenovirus Vectors for Imaging and Gene Therapy of Breast Cancer
    Victor Krasnykh, PhD
    University of Texas M.D. Anderson Cancer Center

    $250,000


    A Lymph Node Targeted Anti-Cancer Drug Delivery System for Breast Cancer Metastases Based on Calcium Phosphate Particulates
    Liisa Kuhn, PhD
    University of Connecticut Health Center

    $250,000


    RNA Interference as a Novel Approach to Target Cyclin E Overexpression in Breast Cancer
    Kaiyi Li, PhD
    Baylor College of Medicine

    $250,000


    Mesenchymal Stem Cells as Cellular Delivery Vehicles for Control of Metastatic Breast Cancer
    Frank Marini, PhD
    University of Texas M.D. Anderson Cancer Center

    $250,000


    Auger Electron Emitters for Breast Cancer Radioimmunotherapy
    M. Jules Mattes, PhD
    Center for Molecular Medicine and Immunology

    $250,000


    The Plasminogen Activator System as a Target for Breast Cancer Virotherapy
    Jaime Merchan, MD, MMSc
    University of Miami

    $250,000


    Development of Selective AP-Site Directed Drugs in Breast Cancer
    Nouri Neamati, PhD
    University of Southern California

    $250,000


    Assessment of Adipose Tissue Engineering to Restore the Postmastectomy Breast
    Charles Patrick Jr, PhD
    University of Texas M.D. Anderson Cancer Center

    $250,000


    Epoxygenase Mechanisms of Breast Cancer Progression
    David Potter, MD, PhD
    Indiana University

    $250,000


    VSV-G Pseudotyped, Semi-Replication-Competent Vector for Breast Cancer Gene Therapy
    Jian Qiao, PhD and MD
    Mayo Clinic

    $250,000


    Interactions of Black Cohosh Extracts with Doxorubicin: Possible Mechanisms
    Sara Rockwell, PhD
    Yale University

    $250,000


    Targeted Immunotherapeutic Strategies in Breast Cancer
    Andrew Scott, MB BS, FRACP
    Ludwig Institute for Cancer Research

    $249,998


    Cyclooxygense-2 Protein and Tamoxifen Resistance in Breast Cancer
    Ana Tari, PhD
    University of Texas M.D. Anderson Cancer Center

    $249,805


    Intensity Modulated Radiotherapy for Treatment of Breast Cancer Patients in Prone Position
    Julia White, MD
    Medical College of Wisconsin

    $249,954


    Optimizing Oral Chemotherapy in Breast Cancer Using Fixed Dose Schedules: The Identification of Predictive Markers of Response and Toxicity to Capecitabine
    Antonio Wolff, MD
    The Sidney Kimmel Cancer Center at Johns Hopkins

    $250,000


    Intensity Modulated Breast Irradiation Under the Guidance of PET/CT Imaging
    Lei Xing, PhD
    Stanford University

    $250,000


    Enhancement of Radiotherapy of Breast Cancer by a Novel Chemoradiosensitizing Agent
    Li-Xi Yang, MD, PhD
    Calfornia Pacific Medical Center Research Institute

    $249,998



    * Pending executed agreement