2004-2005 Grant Cycle : Research Grants Awarded
Biology of Breast Cancer
Characterization of VSV Oncolytic Activity in Breast Cancer Model Systems
Glen Barber, PhD
Paula Faria
University of Miami
$135,000
Radiation and TGF Beta as Mediators of Stromal Activation in Breast Carcinogenesis
Mary Helen Barcellos-Hoff, PhD
Jenny Paupert
Lawrence Berkeley National Labs
$135,000
Role of Small GTPase RhoB in Breast Tumorigenesis
Laura Benjamin, PhD
Shiva Kazerounian
Beth Israel Deaconess Medical Center/Harvard Medical School
$135,000
The Type III TGF-Beta Receptor as a Candidate Tumor Suppressor Gene in Breast Cancer
Gerard Blobe, MD,PhD
Mei Dong
Duke University
$135,000
Crosstalk Between Extrinsic and Intrinsic Caspase Activation Pathways in Doxorubicin-Mediated Sensitization of Breast Cancer Cells to TRAIL-Induced Apoptosis
Matthew Bogyo, PhD
Kelly Boatright
Stanford University School of Medicine
$135,000
LDP1 Directly Links the Tumor Suppressor Protein P53 to Iron Metabolism
Rainer Brachmann, MD
Lawrence Dearth
University of California, Irvine
$133,864
The Differential Effects of Estrogen on Gene Regulation and Apoptosis in the Breast and Bone
Myles Brown, MD
Susan Krum
Dana-Farber Cancer Institute
$135,000
Scaffolding Proteins and Rho Signaling in Breast Cancer
Keith Burridge, PhD
Rafael Garcia-Mata
University of North Carolina at Chapel Hill
$135,000
IRF-1-Dependent Apoptosis and Antiestrogen Sensitivity in Breast Cancer
Robert Clarke, PhD, Dphil
Rebecca Riggins
Georgetown University, Lombardi Comprehensive Cancer Center
$90,000
Identification, Expression Profiling and Functional Analysis of MicroRNAs in Breast Cancer
Charles Cole, PhD
Lorenzo Sempere
Dartmouth Medical School
$134,500
Identification of Substrates of the Her2/neu Tyrosine Kinase in Breast Cancer Cell Lines using Chemical Rescue of a Her2/neu Catalytic Loop Point Mutation
Philip Cole, MD PhD
Ron Bose
Johns Hopkins University
$90,000
Profiling Enzyme Activities in Human Breast Cancer
Benjamin Cravatt, PhD
BinQing Wei
The Scripps Research Institute
$134,925
Investigation of the Role Played by BRCA1 in the Activation of FANCD2 Following Chemotherapy Induced DNA Damage
Alan D'Andrea, MD
Richard Kennedy
Dana-Farber Cancer Institute
$135,000
Regulation of the Cellular Senescence Program by RB Proteins
Brian Dynlacht, PhD
Nathan Lents
New York University School of Medicine
$135,000
Notch Regulation of Epithelial-Mesenchymal Transition During Wound Healing and Migration of Mammary Epithelial Cells
Alan Hall, B.A., PHD.
Karni Schlessinger
University College London, MRC-LMCB
$135,000
An Investigation of p21CIP1 Function During Breast Cancer Metastasis
Rachel Hazan, PhD
James Hulit
Albert Einstein College of Medicine of Yeshiva University
$135,000
DNA Vaccines Against Breast Cancer: Synergy Through Targeting Both Tumor Cells and Tumor Stroma
Alan Houghton, MD
Francesca Orlandi
Sloan-Kettering Institute for Cancer Research
$135,000
Roles of Chk1 Kinase in Breast Cancer Etiology and Therapy
Tony Hunter, PhD
You-Wei Zhang
The Salk Institute for Biological Studies
$135,000
Novel Signaling Mechanisms of CXCR4-induced Chemotaxis
Richard Klemke, PhD
Yingchun Wang
The Regents of the University of California, University of California, San Diego
$135,000
The Role of E2F3 in Breast Cancer
Gustavo Leone, PhD
Shu-Huei Wang
The Ohio State University Research Foundation
$135,000
Synergism Between c-Src and EGFR Intracellular Trafficking in Breast Cancer
Marilyn Resh, AB, PhD
Mrudula Donepudi
Memorial Sloan-Kettering Cancer Center
$135,000
Structure and Biochemistry of the Homologous DNA Recombinase Rad51
Phoebe Rice, PhD
Arabela Grigorescu
University of Chicago
$135,000
Small animal ultrasound to examine the role of AIB1 and its isoform in estrogen receptor alpha-initiated preneoplasia and DCIS
Anna Riegel, MS PhD
Maddalena Tilli
Lombardi Cancer Center
$135,000
The Role of TRAP220 in Estrogen Receptor-Dependent Function and in Mammary Gland Development and Neoplasia
Robert Roeder, PhD
Xiaotiing Zhang
The Rockefeller University
$135,000
Identification and Characterization of Breast Cancer Stem Cells
Jeffrey Rosen, PhD
Mei Zhang
Baylor College of Medicine
$135,000
Tamoxifen Response Pathway Characterization by Reversible Gene Entrapment of Breast Cancer Cells
H. Earl Ruley, PhD
Sarah Donahue
Vanderbilt University Medical Center
$135,000
Genetic Understanding of Locally Advanced Breast Cancer
Robert Schneider, PhD
Ksenia Karpisheva
New York University School of Medicine
$135,000
The Role of Shp2 in the Alpha 6 Beta 4 Integrin-dependent Metastasis
Leslie Shaw, PhD
Udayan Dutta
University of Massachusetts Medical School
$90,000
Structural and Biochemical Characterization of PGC-1a Coactivation of the Tumor Suppressor Protein P53
Bruce Spiegelman, PhD
srikripa devarakonda
Dana-Farber Cancer Institute
$135,000
Delineation of the role of the tumor suppressor BRCA2 in homologous recombination and DNA repair
Patrick Sung, Dphil
Joseph San Filippo
Yale University
$135,000
Chromatin and the Regulation of DNA Double-Strand Breaks
Anne Villeneuve, PhD
Jessica Bessler
Stanford University
$135,000
Disregulation of Stem Cell Self-renewal in Breast Cancer Development
Max Wicha, MD
Suling Liu
University of Michigan
$135,000
Use of Molecular Imaging and Genetic Approaches to Investigate the Role of Tumor Lymphangiogenesis in Breast Cancer Metastasis
Lily Wu, PhD, MD
Yufang Hu
University of California, Los Angeles
$90,000
Early Detections, Diagnosis, and Prognosis
Development of Marlers that Predict Resistance to Omnitarg in Breast Cancer
Joe Gray, PhD
Yinghui Guan
Ed Lawrence Berkeley National Laboratory
$135,000
Etiology
Estrogen Receptor AF-1 Interacting Proteins and Peptides
Geoffrey Greene, PhD
Hoyee Leong
University of Chicago
$135,000
Orphan Nuclear Receptor PXR in Estrogen Deprivation and Breast Cancer
Wen Xie, PhD, MD
Haibiao Gong
University of Pittsburgh
$135,000
Prevention
Targeting a Novel Breast Differentiation Antigen for Breast Cancer Immunotherapy
Stanley Riddell, MD
Wei Wang
Fred Hutchinson Cancer Research Center
$135,000
Scientific Model Systems
Improved Xenotransplant Model for Human Breast Cancer
Hallgeir Rui, PhD, MD
Fransiscus Utama
Georgetown University
$135,000
Treatment
Antitumoral Efficacy of Novel Inhibitors of the Fatty Acid Synthase
Ramon Colomer, medical doctor (oncologist) and PhD.
RUT PORTA
Intitut Catala d'Oncologia - Hospital Universitari Dr.Josep Trueta
$135,000
E2F-1 and Telomeres: A Combined Strategy for Treatment and Prognosis of Breast Cancer
Kelly Hunt, MD
Michelle Fanale
University of Texas M.D. Anderson Cancer Center
$135,000
Targeting Retrovirus Replication for Gene Therapy of Breast Cancer
Noriyuki Kasahara, MD, PhD
Kei Hiraoka
University of California, Los Angeles
$135,000
Total Synthesis of Apoptolidin and Analogs
Gary Molander, PhD
Frieman Bryan
University of Pennsylvania
$125,238
* Pending executed agreement
