Susan G Komen  
I've Been Diagnosed With Breast Cancer Someone I Know Was Diagnosed Share Your Story Join Us And Stay Informed Donate To End Breast Cancer
    Home > Research & Grants > Grants Program > Research Grants > Research Grants Awarded > Pathobiology : 2007-2008

    Research Grants Awarded

    2007-2008 Grant Cycle : Research Grants Awarded

    Pathobiology

    An Integrated Approach Towards The Eradication Of Her2-Driven Breast Cancer
    Mark Moasser*, M.D.
    James A Wells, MD
    John Kuriyan, PhD

    University of California at San Francisco
    Promise Grant
    $1,000,000


    Micro-RNA Regulation Of Oncogenes And Tumor Suppressors In Breast Cancer
    Andrei Goga*, M.D., Ph.D.
    University of California at San Francisco
    Investigator Initiated Research
    $600,000


    Role Of Coup-Tfii In Endocrine-Responsive And Resistant Breast Cancer
    Carolyn Klinge, Ph.D.
    University of Louisville at School of Medicine
    Investigator Initiated Research
    $600,000
    Co-funded by Komen Louisville Affiliate

    Genome Maintenance In Breast Cancer
    David Cortez, Ph.D.
    Vanderbilt University Medical Center
    Investigator Initiated Research
    $600,000
    Co-funded by Komen Greater Nashville Affiliate

    Regulated Antizyme Expression For The Prevention And Treatment Of Breast Cancer
    David Feith, Ph.D.
    Pennsylvania State University College of Medicine
    Investigator Initiated Research
    $600,000


    Analysis Of Telomere Dysfunction For Early Breast Cancer Detection
    David Gilley, Ph.D.
    Indiana University, School of Medicine
    Investigator Initiated Research
    $600,000


    Evaluating The Role Of Mps1 Over-Expression In Breast Cancer
    Edward Gabrielson, Ph.D.
    Johns Hopkins University, School of Medicine
    Investigator Initiated Research
    $600,000


    Admixture Mapping For Breast Cancer Susceptibility Genes Among African American Women
    Elad Ziv*, M.D.
    University of California at San Francisco
    Investigator Initiated Research
    $596,228


    Genetic Risk Factors For Brca1 Deficient And Basal Breast Cancer
    Fergus Couch, Ph.D.
    Mayo Clinic and Foundation, Rochester
    Investigator Initiated Research
    $600,000


    Validating Myc As A Therapeutic Target In Breast Cancer
    Gerard Evan, Ph.D.
    University of California at San Francisco
    Investigator Initiated Research
    $600,000


    A Novel Genomic Approach To Finding New Genes For Inherited Breast Cancer:Rare Structural Variants In High-Risk Families
    Mary Claire King, Ph.D.
    University of Washington at Seattle
    Investigator Initiated Research
    $600,000


    Cyclin D1-Cdk4 Kinase In Human Breast Cancers
    Piotr Sicinski*, M.D., Ph.D.
    Dana-Farber Cancer Institute
    Investigator Initiated Research
    $600,000


    Examining A Novel Link Between Rho Gtpases And The Metabolic Machinery Of Human Breast Cancer Cells
    Richard Cerione, Ph.D.
    Cornell University, Ithaca
    Investigator Initiated Research
    $600,000


    Genetic Characterization Of Breast Cancer Risk In Families
    Richard Kerber, Ph.D.
    University of Utah at Huntsman Cancer Institute
    Investigator Initiated Research
    $528,629


    Inhibition Of Lysine Specific Demethylase 1 (Lsd1) As A Strategy For Re-Expression Of Epigenetically Silenced Genes In Breast Cancer
    Robert Casero, Ph.D.
    Johns Hopkins University
    Investigator Initiated Research
    $600,000


    Disruption Of Tgf-Beta/Smad Signaling Events For The Therapy Of Breast Cancer Metastasis
    Sam Thiagalingam, Ph.D.
    Boston University School of Medicine
    Investigator Initiated Research
    $600,000


    Tyrosine Phosphorylation And Functional Regulation Of Pcna In Breast Cancer
    Shao-Chun Wang, Ph.D.
    University of Cincinnati
    Investigator Initiated Research
    $600,000
    Co-funded by Komen Greater Cincinnati Affiliate

    Modulation Of Obesity-Induced Breast Cancer Risk By Metformin
    Steven Anderson*, Ph.D.
    University of Colorado Health Sciences Center
    Investigator Initiated Research
    $599,999


    Role Of Estrogen In Breast Cancer Gene Amplification
    Susan Gerbi, Ph.D.
    Brown University
    Investigator Initiated Research
    $600,000


    Molecular Biological Studies Of DCIS Induced By Oncogenic Kinase
    Toru Ouchi, Ph.D.
    Evanston Northwestern Healthcare Research Institute
    Investigator Initiated Research
    $600,000


    Regulation Of Her2/Neu And Her3 Membrane Expression In Breast Cancer Therapy
    Wei Chen, Ph.D.
    Duke University Medical Center
    Investigator Initiated Research
    $600,000


    Controlling Mammary Luminal And Basal Progenitor Cell Proliferation, Differentiation, And Tumorigenesis
    Yue Xiong, Ph.D.
    University of North Carolina at Chapel Hill
    Investigator Initiated Research
    $600,000


    Bionergetic Control Of Breast Cancer Growth By The Transcriptional Co Activator Pgc1Alpha
    Geoffrey Girnun, Ph.D.
    University of Maryland at School of Medicine
    Career Catalyst Research
    $450,001


    Investigation Of Oncogenic Properties And Therapeutic Application Of Pik3Ca Mutations In Breast Cancer
    Guojun Wu, Ph.D.
    Wayne State University, Karmanos Cancer Institute
    Career Catalyst Research
    $450,000
    Co-funded by Komen Greater Lansing Affiliate

    Mechanisms Of Telomere Dysfunction In Breast Cancer
    Hiromi Tanaka*, Ph.D.
    Indiana University, School of Medicine
    Career Catalyst Research
    $450,000


    Targeting Inflammation In Breast Cancer
    Kathryn Schwertfeger, Ph.D.
    University of Minnesota at Twin Cities
    Career Catalyst Research
    $450,000


    Palb2 ? A New Hereditary Cancer Gene: Implications For Treatment
    Marc Tischkowitz, M.D., Ph.D.
    Sir Mortimer B. Davis - Jewish General Hospital, Lady Davis Institute for Medical Research
    Career Catalyst Research
    $290,852


    Function And Mechanism(S) For E-Cadherin Loss In Breast Cancer
    Sabine Brouxhon, M.D.
    University of Rochester School of Medicine
    Career Catalyst Research
    $299,872
    Co-funded by Komen Western New York Affiliate

    Role Of Autophagy In Breast Cancer Cell Death In Response To Chemotherapy
    Wei-Xing Zong, Ph.D.
    State University of New York at Stony Brook
    Career Catalyst Research
    $450,000


    Critical Role Of Integrin-Associated Cd151 In Progression Of Er-Negative Mammary Tumors
    Xiuwei Yang, Ph.D.
    Dana-Farber Cancer Institute
    Career Catalyst Research
    $448,371


    Regulation Of Breast Cancer Progression Through The Transcriptional Repressor Hbp1
    Amy Yee, Ph.D.
    Teeru Bihani, PhD
    Tufts University
    Postdoctoral Fellowships
    $180,000


    Dbc2/Rhobtb2: An Atypical Rho Gtpase And Tumor Suppressor In Breast Cancer Development?
    Channing Der, Ph.D.
    Cercina Onesto, PhD
    University of North Carolina at Chapel Hill
    Postdoctoral Fellowships
    $180,000
    Co-funded by Komen Charlotte Affiliate

    Study Of Mammary Stem Cells To Examine Mechanism of Parity-Induced Protection Against Breast Cancer
    Debananda Pati, Ph.D.
    Rene Meyer, PhD
    Baylor College of Medicine
    Postdoctoral Fellowships
    $180,000


    The Contribution Of The Tex14 Kinase To Chromosomal Instability And Breast Cancer
    Fergus Couch, Ph.D.
    Gourish Mondal, PhD
    Mayo Clinic and Foundation, Rochester
    Postdoctoral Fellowships
    $180,000


    Extracellular Superoxide Dismutase Plus Pi-88 As A Novel Anti-Metastatic Therapy For Breast Cancer
    Frederick Domann, Ph.D.
    Melissa (Lai Tee) Teoh, PhD
    University of Iowa at Carver College of Medicine
    Postdoctoral Fellowships
    $180,000
    Co-funded by Komen Des Moines Affiliate

    Elucidating The Tumor Suppressor Function Of Tbetariii In Breast Carcinogenesis
    Gerard Blobe, Ph.D.
    Catherine E Gatza, PhD
    Duke University, School of Medicine
    Postdoctoral Fellowships
    $180,000


    Humanized Mouse Model For Analysis Of Human Breast Cancer Xenotransplants
    Hallgeir Rui, M.D., Ph.D.
    Ning Yang, MD, PhD
    Thomas Jefferson University
    Postdoctoral Fellowships
    $180,000


    Role Of Adiponectin In Breast Tumor Formation And Rrogression
    Harvey Lodish, Ph.D.
    Yutong Sun, PhD
    Whitehead Institute for Biomedical Research
    Postdoctoral Fellowships
    $180,000


    Brca1-Mediated Regulation Of Oxidative DNA Damage In Breast Cancer
    James Ford, Ph.D.
    Elizabeth Alli, PhD
    Stanford University, School of Medicine
    Postdoctoral Fellowships
    $180,000


    Critical Roles Of Dmp1 In The Prevention Of Cyclin D1-Induced Breast Cancer
    Kazushi Inoue, M.D., Ph.D.
    Pankaj Taneja, MD, PhD
    Wake Forest University Health Sciences
    Postdoctoral Fellowships
    $180,000


    Epigenetic Determinants Of Progenitor Cell Function In Normal And Neoplastic Human Breast Epithelium
    Kornelia Polyak, M.D., Ph.D.
    Reo Maruyama, MD, PhD
    Dana-Farber Cancer Institute
    Postdoctoral Fellowships
    $180,000


    Tumor-Associated Macrophage-Mediated Inflammatory Responses In Serm "Resistant" Breast Cancer As A Therapeutic Target
    Michael Rosenfeld, M.D.
    Chunru Lin, MD
    University of California at San Diego
    Postdoctoral Fellowships
    $180,000


    Identification And Targeting Of Adipose Stem Cell Markers For Breast Cancer Therapy
    Mikhail Kolonin, Ph.D.
    Yan Zhang, PhD
    University of Texas at Health Science Center at Houston
    Postdoctoral Fellowships
    $180,000


    Cell-Cell Interactions And Eph/Eprhin Signaling Axis In Mammary Gland Branching Morphogenesis And Tumorigenesis
    Mina Bissell*, Ph.D.
    Carole Berruyer-Pouyet, PhD Lawrence Berkeley National Laboratory
    Postdoctoral Fellowships
    $118,322


    Role Of The Tumor Suppressors Brca2 And Palb2 In Chromosome Damage Repair
    Patrick Sung, Ph.D.
    Hengyao Niu, PhD Yale University, School of Medicine
    Postdoctoral Fellowships
    $180,000


    Disrupted Estrogen Signaling Pathways Collaborate With Loss Of P53 In The Development Of Preneoplasia In Breast Cancer
    Priscilla Furth, M.D.
    Edgar S Diaz-Cruz, MD Georgetown University, Lombardi Comprehensive Cancer Center
    Postdoctoral Fellowships
    $180,000


    A Functional Genomic Approach To Identify Potential Breast Cancer Therapeutic Targets
    Stephen Elledge*, Ph.D.
    Nicole L Solimini, PhD
    Brigham and Women's Hospital
    Postdoctoral Fellowships
    $180,000



    * Pending executed agreement