2007-2008 Grant Cycle : Research Grants Awarded
Pathobiology
An Integrated Approach Towards The Eradication Of Her2-Driven Breast Cancer
Mark Moasser*, M.D.
James A Wells, MD
John Kuriyan, PhD
University of California at San Francisco
Promise Grant
$1,000,000
Micro-RNA Regulation Of Oncogenes And Tumor Suppressors In Breast Cancer
Andrei Goga*, M.D., Ph.D.
University of California at San Francisco
Investigator Initiated Research
$600,000
Role Of Coup-Tfii In Endocrine-Responsive And Resistant Breast Cancer
Carolyn Klinge, Ph.D.
University of Louisville at School of Medicine
Investigator Initiated Research
$600,000
Co-funded by Komen Louisville Affiliate
Genome Maintenance In Breast Cancer
David Cortez, Ph.D.
Vanderbilt University Medical Center
Investigator Initiated Research
$600,000
Co-funded by Komen Greater Nashville Affiliate
Regulated Antizyme Expression For The Prevention And Treatment Of Breast Cancer
David Feith, Ph.D.
Pennsylvania State University College of Medicine
Investigator Initiated Research
$600,000
Analysis Of Telomere Dysfunction For Early Breast Cancer Detection
David Gilley, Ph.D.
Indiana University, School of Medicine
Investigator Initiated Research
$600,000
Evaluating The Role Of Mps1 Over-Expression In Breast Cancer
Edward Gabrielson, Ph.D.
Johns Hopkins University, School of Medicine
Investigator Initiated Research
$600,000
Admixture Mapping For Breast Cancer Susceptibility Genes Among African American Women
Elad Ziv*, M.D.
University of California at San Francisco
Investigator Initiated Research
$596,228
Genetic Risk Factors For Brca1 Deficient And Basal Breast Cancer
Fergus Couch, Ph.D.
Mayo Clinic and Foundation, Rochester
Investigator Initiated Research
$600,000
Validating Myc As A Therapeutic Target In Breast Cancer
Gerard Evan, Ph.D.
University of California at San Francisco
Investigator Initiated Research
$600,000
A Novel Genomic Approach To Finding New Genes For Inherited Breast Cancer:Rare Structural Variants In High-Risk Families
Mary Claire King, Ph.D.
University of Washington at Seattle
Investigator Initiated Research
$600,000
Cyclin D1-Cdk4 Kinase In Human Breast Cancers
Piotr Sicinski*, M.D., Ph.D.
Dana-Farber Cancer Institute
Investigator Initiated Research
$600,000
Examining A Novel Link Between Rho Gtpases And The Metabolic Machinery Of Human Breast Cancer Cells
Richard Cerione, Ph.D.
Cornell University, Ithaca
Investigator Initiated Research
$600,000
Genetic Characterization Of Breast Cancer Risk In Families
Richard Kerber, Ph.D.
University of Utah at Huntsman Cancer Institute
Investigator Initiated Research
$528,629
Inhibition Of Lysine Specific Demethylase 1 (Lsd1) As A Strategy For Re-Expression Of Epigenetically Silenced Genes In Breast Cancer
Robert Casero, Ph.D.
Johns Hopkins University
Investigator Initiated Research
$600,000
Disruption Of Tgf-Beta/Smad Signaling Events For The Therapy Of Breast Cancer Metastasis
Sam Thiagalingam, Ph.D.
Boston University School of Medicine
Investigator Initiated Research
$600,000
Tyrosine Phosphorylation And Functional Regulation Of Pcna In Breast Cancer
Shao-Chun Wang, Ph.D.
University of Cincinnati
Investigator Initiated Research
$600,000
Co-funded by Komen Greater Cincinnati Affiliate
Modulation Of Obesity-Induced Breast Cancer Risk By Metformin
Steven Anderson*, Ph.D.
University of Colorado Health Sciences Center
Investigator Initiated Research
$599,999
Role Of Estrogen In Breast Cancer Gene Amplification
Susan Gerbi, Ph.D.
Brown University
Investigator Initiated Research
$600,000
Molecular Biological Studies Of DCIS Induced By Oncogenic Kinase
Toru Ouchi, Ph.D.
Evanston Northwestern Healthcare Research Institute
Investigator Initiated Research
$600,000
Regulation Of Her2/Neu And Her3 Membrane Expression In Breast Cancer Therapy
Wei Chen, Ph.D.
Duke University Medical Center
Investigator Initiated Research
$600,000
Controlling Mammary Luminal And Basal Progenitor Cell Proliferation, Differentiation, And Tumorigenesis
Yue Xiong, Ph.D.
University of North Carolina at Chapel Hill
Investigator Initiated Research
$600,000
Bionergetic Control Of Breast Cancer Growth By The Transcriptional Co Activator Pgc1Alpha
Geoffrey Girnun, Ph.D.
University of Maryland at School of Medicine
Career Catalyst Research
$450,001
Investigation Of Oncogenic Properties And Therapeutic Application Of Pik3Ca Mutations In Breast Cancer
Guojun Wu, Ph.D.
Wayne State University, Karmanos Cancer Institute
Career Catalyst Research
$450,000
Co-funded by Komen Greater Lansing Affiliate
Mechanisms Of Telomere Dysfunction In Breast Cancer
Hiromi Tanaka*, Ph.D.
Indiana University, School of Medicine
Career Catalyst Research
$450,000
Targeting Inflammation In Breast Cancer
Kathryn Schwertfeger, Ph.D.
University of Minnesota at Twin Cities
Career Catalyst Research
$450,000
Palb2 ? A New Hereditary Cancer Gene: Implications For Treatment
Marc Tischkowitz, M.D., Ph.D.
Sir Mortimer B. Davis - Jewish General Hospital, Lady Davis Institute for Medical Research
Career Catalyst Research
$290,852
Function And Mechanism(S) For E-Cadherin Loss In Breast Cancer
Sabine Brouxhon, M.D.
University of Rochester School of Medicine
Career Catalyst Research
$299,872
Co-funded by Komen Western New York Affiliate
Role Of Autophagy In Breast Cancer Cell Death In Response To Chemotherapy
Wei-Xing Zong, Ph.D.
State University of New York at Stony Brook
Career Catalyst Research
$450,000
Critical Role Of Integrin-Associated Cd151 In Progression Of Er-Negative Mammary Tumors
Xiuwei Yang, Ph.D.
Dana-Farber Cancer Institute
Career Catalyst Research
$448,371
Regulation Of Breast Cancer Progression Through The Transcriptional Repressor Hbp1
Amy Yee, Ph.D.
Teeru Bihani, PhD
Tufts University
Postdoctoral Fellowships
$180,000
Dbc2/Rhobtb2: An Atypical Rho Gtpase And Tumor Suppressor In Breast Cancer Development?
Channing Der, Ph.D.
Cercina Onesto, PhD
University of North Carolina at Chapel Hill
Postdoctoral Fellowships
$180,000
Co-funded by Komen Charlotte Affiliate
Study Of Mammary Stem Cells To Examine Mechanism of Parity-Induced Protection Against Breast Cancer
Debananda Pati, Ph.D.
Rene Meyer, PhD
Baylor College of Medicine
Postdoctoral Fellowships
$180,000
The Contribution Of The Tex14 Kinase To Chromosomal Instability And Breast Cancer
Fergus Couch, Ph.D.
Gourish Mondal, PhD
Mayo Clinic and Foundation, Rochester
Postdoctoral Fellowships
$180,000
Extracellular Superoxide Dismutase Plus Pi-88 As A Novel Anti-Metastatic Therapy For Breast Cancer
Frederick Domann, Ph.D.
Melissa (Lai Tee) Teoh, PhD
University of Iowa at Carver College of Medicine
Postdoctoral Fellowships
$180,000
Co-funded by Komen Des Moines Affiliate
Elucidating The Tumor Suppressor Function Of Tbetariii In Breast Carcinogenesis
Gerard Blobe, Ph.D.
Catherine E Gatza, PhD
Duke University, School of Medicine
Postdoctoral Fellowships
$180,000
Humanized Mouse Model For Analysis Of Human Breast Cancer Xenotransplants
Hallgeir Rui, M.D., Ph.D.
Ning Yang, MD, PhD
Thomas Jefferson University
Postdoctoral Fellowships
$180,000
Role Of Adiponectin In Breast Tumor Formation And Rrogression
Harvey Lodish, Ph.D.
Yutong Sun, PhD
Whitehead Institute for Biomedical Research
Postdoctoral Fellowships
$180,000
Brca1-Mediated Regulation Of Oxidative DNA Damage In Breast Cancer
James Ford, Ph.D.
Elizabeth Alli, PhD
Stanford University, School of Medicine
Postdoctoral Fellowships
$180,000
Critical Roles Of Dmp1 In The Prevention Of Cyclin D1-Induced Breast Cancer
Kazushi Inoue, M.D., Ph.D.
Pankaj Taneja, MD, PhD
Wake Forest University Health Sciences
Postdoctoral Fellowships
$180,000
Epigenetic Determinants Of Progenitor Cell Function In Normal And Neoplastic Human Breast Epithelium
Kornelia Polyak, M.D., Ph.D.
Reo Maruyama, MD, PhD
Dana-Farber Cancer Institute
Postdoctoral Fellowships
$180,000
Tumor-Associated Macrophage-Mediated Inflammatory Responses In Serm "Resistant" Breast Cancer As A Therapeutic Target
Michael Rosenfeld, M.D.
Chunru Lin, MD
University of California at San Diego
Postdoctoral Fellowships
$180,000
Identification And Targeting Of Adipose Stem Cell Markers For Breast Cancer Therapy
Mikhail Kolonin, Ph.D.
Yan Zhang, PhD
University of Texas at Health Science Center at Houston
Postdoctoral Fellowships
$180,000
Cell-Cell Interactions And Eph/Eprhin Signaling Axis In Mammary Gland Branching Morphogenesis And Tumorigenesis
Mina Bissell*, Ph.D.
Carole Berruyer-Pouyet, PhD
Lawrence Berkeley National Laboratory
Postdoctoral Fellowships
$118,322
Role Of The Tumor Suppressors Brca2 And Palb2 In Chromosome Damage Repair
Patrick Sung, Ph.D.
Hengyao Niu, PhD
Yale University, School of Medicine
Postdoctoral Fellowships
$180,000
Disrupted Estrogen Signaling Pathways Collaborate With Loss Of P53 In The Development Of Preneoplasia In Breast Cancer
Priscilla Furth, M.D.
Edgar S Diaz-Cruz, MD
Georgetown University, Lombardi Comprehensive Cancer Center
Postdoctoral Fellowships
$180,000
A Functional Genomic Approach To Identify Potential Breast Cancer Therapeutic Targets
Stephen Elledge*, Ph.D.
Nicole L Solimini, PhD
Brigham and Women's Hospital
Postdoctoral Fellowships
$180,000
* Pending executed agreement
