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    Home > Research & Grants > Grants Program > Research Grants > Research Grants Awarded > Immunotherapies : 2007-2008

    Research Grants Awarded

    2007-2008 Grant Cycle : Research Grants Awarded

    Immunotherapies

    Novel Targets For Treatment And Detection Of Inflammatory Breast Cancer
    Fredika Robertson, Ph.D.
    Massimo Cristofanilli, PhD M.D. Anderson Cancer Center, University of Texas
    Promise Grant
    $7,500,000


    Optimizing Endocrine Therapies For The Individual Patient With Breast Cancer: Identifying Targets For Tailored Treatment
    Giuseppe Viale*, M.D.
    Olivia Pagani, MD
    Meredith Regan, D.Sc
    European Institute of Oncology
    Promise Grant
    $3,929,682


    Using Genomics And Proteomics To Develop Effective Therapies For Er-Negative Breast Cancer
    Powel Brown*, M.D., Ph.D.
    Gordon B Mills, MD, PhD
    Baylor College of Medicine
    Promise Grant
    $7,138,690


    Preventing Basal Breast Cancer Recurrence
    Brian Law, Ph.D.
    University of Florida
    Investigator Initiated Research
    $600,000
    Co-funded by Komen Central Florida Affiliate

    A Novel Preemptive Strategic Combinational Molecular Therapeutics Targeting Cancer Bioenergetics And Growth Regulatory Signaling Network In Breast Cancer
    Gordon Mills, M.D., Ph.D.
    M.D. Anderson Cancer Center, University of Texas
    Investigator Initiated Research
    $600,000


    Chk1- And Pi3K-Pathways As Therapeutic Targets In Triple Negative Breast Cancers
    Helen Piwnica-Worms, Ph.D.
    Washington University at St. Louis, School of Medicine
    Investigator Initiated Research
    $600,000


    Systematic Characterization Of Dasatinib Sensitivity And Resistance In Breast Cancer Cells: Rationale For Patient Selection And Treatment Design
    Jun Zhu, Ph.D.
    Duke University Medical Center
    Investigator Initiated Research
    $600,000


    The Transmembrane Protein Trop-2: An Attractive Target For Breast Cancer Therapy
    Loren Michel, M.D.
    Washington University at St. Louis, School of Medicine
    Investigator Initiated Research
    $600,000


    Combination Chemo-Immunotherapy For Established Breast Cancer
    Mark Smyth*, Ph.D.
    University of Melbourne
    Investigator Initiated Research
    $598,492


    Targeting Her2 Signalling By Alphaviral-Based Immunotherapy Plus Tyrosine Kinase Inhibition
    Michael Morse*, M.D.
    Duke University Medical Center
    Investigator Initiated Research
    $512,984


    Anti-Plgf, A Potent And Safe Antiangiogenic Strategy In Combination With Anthracyclines For Breast Cancer
    Peter Carmeliet*, M.D., Ph.D.
    Katholieke Universiteit Leuven-Vib
    Investigator Initiated Research
    $576,000


    Molecular Characterization Of Disseminated Tumor Cells
    Rebecca Aft, M.D., Ph.D.
    Washington University in St. Louis
    Investigator Initiated Research
    $600,000


    Promotion Of Anti-Tumor Immune Responses By Conversion Of Tumor-Associated Macrophages To Inflammatory Phenotype
    Robert Stout, Ph.D.
    University of Louisville
    Investigator Initiated Research
    $600,000


    Targeting DNA Repair Deficienies In Human Breast Cancer
    Simon Powell, M.D., Ph.D.
    Washington University at St. Louis, School of Medicine
    Investigator Initiated Research
    $600,000


    Interfering Breast Cancer Metastasis By Blocking Ngal Function
    Yun Wu, M.D., Ph.D.
    M.D. Anderson Cancer Center, University of Texas
    Investigator Initiated Research
    $600,000


    Targeting Death Pathways By Tumor-Targeting Sirna-Nanovectors As Novel Molecular Therapy For Primary And Metastatic Breast Cancer
    Bulent Ozpolat, M.D., Ph.D.
    M.D. Anderson Cancer Center, University of Texas
    Career Catalyst Research
    $406,579


    Therapeutic Strategies To Alter Gene Expression In Breast Cancer
    Christine Stellrecht, Ph.D.
    M.D. Anderson Cancer Center, University of Texas
    Career Catalyst Research
    $450,000


    Enrichment Of Rare Circulating Antigen-Specific Effector T Cells By Mch/Peptide Tetramer Immunomagnetic Sorting And Hyperexpansion For Therapy Of Breast Cancer
    Li-Xin Wang, M.D., Ph.D.
    Cleveland Clinic Foundation
    Career Catalyst Research
    $449,447
    Co-funded by Komen Northeast Ohio Affiliate

    Combination Therapy For Treatment Of Hormone-Resistant Breast Cancers
    Sarah Aiyar, Ph.D.
    University of Virginia at School of Medicine
    Career Catalyst Research
    $449,997


    The Potential Of Cdk1 Inhibition To Sensitize Breast Cancer Cells To Dna Damaging Treatments Through Loss Of Brca1 Function.
    Geoffrey Shapiro, M.D., Ph.D.
    Neil Johnson, PhD
    Dana-Farber Cancer Institute
    Postdoctoral Fellowships
    $120,000


    Enhanced Immunotherapy Of Breast Cancer Using Modified Tlr And Rlr Pathway Activating Adenoviral Vaccines Targeting Her2/Neu.
    Herbert Lyerly, Ph.D.
    Zachary C Hartman, PhD Duke University Medical Center
    Postdoctoral Fellowships
    $180,000


    Genetic Determinants Of Chemosensitivity In Triple Negative Breast Cancer Cells
    James Ford, Ph.D.
    Kedar Hastak, PhD
    Stanford University, School of Medicine
    Postdoctoral Fellowships
    $180,000


    Characterization Of Trps-1 As Novel Active Vaccine Target For Breast Cancer Immunotherapy
    Laszlo Radvanyi, Ph.D.
    Sheng Wu, PhD
    M.D. Anderson Cancer Center, University of Texas
    Postdoctoral Fellowships
    $180,000


    Gene-Signature Targeting As A Novel Approach For Treating Breast Cancer
    Shiaw-Yih Lin, Ph.D.
    Guang Peng, PhD
    M.D. Anderson Cancer Center, University of Texas
    Postdoctoral Fellowships
    $120,000


    Novel Combination Therapy Against Lethal Breast Cancer
    Surinder Batra, Ph.D.
    Moorthy Palanimuthu Ponnusamy, PhD
    University of Nebraska
    Postdoctoral Fellowships
    $180,000
    Co-funded by Komen Nebraska Affiliate

    Preclinical Development Of An Innovative Mammaglobin-A Single Chain Trimer Dna Vaccine
    William Gillanders, M.D.
    Lijin Li, MD Washington University in St. Louis
    Postdoctoral Fellowships
    $180,000



    * Pending executed agreement