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    Home > Research & Grants > Grants Program > Research Grants > Research Grants Awarded > Endocrine Therapies : 2007-2008

    Research Grants Awarded

    2007-2008 Grant Cycle : Research Grants Awarded

    Endocrine Therapies

    Synergistic Cooperation Of Snail And Beta-Catenin In The Initiation Of Breast Cancer Metastasis
    Binhua Zhou, M.D., Ph.D.
    University of Texas at Medical Branch, Galveston
    Investigator Initiated Research
    $600,000


    The Prognostic And Therapeutic Implications Of Bone Marrow-Derived Progenitor Cells In Breast Cancer Invasion And Metastasis
    David Lyden, M.D., Ph.D.
    Cornell University, Weill Medical College
    Investigator Initiated Research
    $600,000


    Constitutively Active Erythropoietin Receptor Variants As Novel Therapeutic Targets In Breast Cancer
    Geza Acs, M.D., Ph.D.
    H. Lee Moffitt Cancer Center & Research Institute
    Investigator Initiated Research
    $595,811


    Role Of The Fn14/Nf-Kb Signaling Pathway In Her2-Positive Breast Cancer
    Jeffrey Winkles, Ph.D.
    University of Maryland at Baltimore
    Investigator Initiated Research
    $600,000


    Wnt/B-Catenin And Egfr Signaling In The Metastasis Of Antiestrogen Resistant Breast Cancer To Bone
    John Foley, Ph.D.
    Indiana University, School of Medicine
    Investigator Initiated Research
    $463,499
    Co-funded by Komen Indianapolis Affiliate

    Targeted Therapy Of Chemoresistant And Metastatic Breast Cancer
    Kapil Mehta, Ph.D.
    M.D. Anderson Cancer Center, University of Texas
    Investigator Initiated Research
    $582,064


    Targeting Notch Signaling And Hepatocyte Growth Factor In Breast Cancer
    Kimberly Foreman, Ph.D.
    Loyola University, Chicago
    Investigator Initiated Research
    $586,581


    Targeting Aberrant Wnt Signaling In Breast Cancer
    Michael Kahn, Ph.D.
    University of Southern California (USC), Keck School of Medicine
    Investigator Initiated Research
    $600,000


    Inflammation And Maspin In Breast Cancer Metastasis
    Ming Zhang, Ph.D.
    Northwestern University, Feinberg School of Medicine
    Investigator Initiated Research
    $600,000


    Clinical And Biologic Effects Of Metformin In Early Stage Breast Cancer
    Pamela Goodwin, M.D.
    Samuel Lunenfeld Research Institute at Mount Sinai Hospital, University of Toronto
    Investigator Initiated Research
    $495,374


    Hypoxic Response And Inflammation: Role In Breast Cancer Progression.
    Randall Johnson, Ph.D.
    University of California at San Diego
    Investigator Initiated Research
    $600,000


    Genetic Analysis Of Jagged1 & Notch1, Genes Implicated In Aggressive Breast Cancer
    Sean Egan*, Ph.D.
    The Hospital for Sick Children
    Investigator Initiated Research
    $595,274


    A Novel Approach To Reduce The Side Effects And Resistance Associated With Aromatase Inhibitor Therapy
    Shiuan Chen, Ph.D.
    City of Hope Beckman Research Institute
    Investigator Initiated Research
    $600,000


    The Role Of Msp In Expanding Breast Tumor Stem Cells And Promoting Metastasis
    Alana Welm, Ph.D.
    University of Utah at Huntsman Cancer Institute
    Career Catalyst Research
    $450,000


    Targeting Advanced Breast Cancer Metastasis
    Emily Chen, Ph.D.
    State University of New York at Stony Brook
    Career Catalyst Research
    $300,000


    The Epigenetic Impact Of Cancer Associated-Fibroblasts On Breast Neoplasm.
    Huey-Jen Lin*, Ph.D.
    Ohio State University, College of Medicine
    Career Catalyst Research
    $450,000


    The Role Of Pmca2 In Mammary Tumorigenesis
    Joshua VanHouten, Ph.D.
    Yale University, School of Medicine
    Career Catalyst Research
    $450,000


    Transphosphorylation Of The Egfr By Met And Other Receptor Tyrosine Kinases In Breast Cancer.
    Julie Boerner, Ph.D.
    Wayne State University, Karmanos Cancer Institute
    Career Catalyst Research
    $450,000
    Co-funded by Komen Detroit Race for the Cure

    Osteoblastic Egfr Signaling In Breast Cancer Bone Metastasis
    Ling Qin, Ph.D.
    University of Medicine & Dentistry of New Jersey, Robert Wood Johnson Medical School
    Career Catalyst Research
    $450,000
    Co-funded by Komen Cerntral and South New Jersey A

    Characterization Of The Molecular And Biological Role That Lip Plays In Metastatic Breast Cancer
    Cynthia Zahnow, Ph.D.
    Huili Li, PhD
    Johns Hopkins University, School of Medicine
    Postdoctoral Fellowships
    $180,000


    Characterizing Mechanisms That Regulate Cdc42 Activation In Breast Cancer
    Elizabeth Sztul, Ph.D.
    Melanie L Styers, PhD
    University of Alabama at Birmingham
    Postdoctoral Fellowships
    $120,000


    Targeting Host And Tumoral Mmp-13 In Primary Breast Cancer And Bone Metastasis.
    Erik Thompson, Ph.D.
    Manisha H Shah, Ph.D. University of Melbourne
    Postdoctoral Fellowships
    $180,000


    From Cell Culture To Mouse Models - Determining The Role Of Klf8 Transcription Factor In Human Breast Cancer Metastasis
    Jihe Zhao, M.D.,Ph.D.
    Xianhui Wang, MD, PhD
    Albany Medical College
    Postdoctoral Fellowships
    $180,000


    Identifying Causes Of Aberrant Glycoprotein Processing And Altered Cell Adhesion In Breast Carcinomas.
    John Muschler*, Ph.D.
    Armin Akhavan, PhD
    California Pacific Medical Center
    Postdoctoral Fellowships
    $180,000


    The Role Of Giv/Girdin And G Proteins In Metastatic Progression Of Breast Cancer
    Marilyn Farquhar, Ph.D.
    Mikel Garcia-Marcos, PhD
    University of California at San Diego
    Postdoctoral Fellowships
    $180,000


    A Src Driven Biomarker And Mediator Of Breast Cancer Metastasis
    Mark Moasser*, Ph.D.
    Danislav S Spassov, MD
    University of California at San Francisco
    Postdoctoral Fellowships
    $180,000


    Synergistic Roles Of The Biophysical And Cellular Microenvironments In Breast Cancer Invasion And Metastasis
    Melody Swartz, Ph.D.
    Adrian C Shieh, PhD
    Ecole Polytechnique Federale de Lausanne
    Postdoctoral Fellowships
    $150,000


    Role Of Ikk/Nf-Kappab/Bmi-1 In Mammary Carcinogenesis And Metastasis
    Michael Karin, Ph.D.
    Weizhou Zhang, PhD University of California at San Diego
    Postdoctoral Fellowships
    $180,000


    Role Of The Spdef Transcription Factor In Breast Cancer And Its Putative Implication In The Estrogen-Mediated Transcriptional Network
    Myles Brown, Ph.D.
    Gilles Buchwalter, PhD Dana-Farber Cancer Institute
    Postdoctoral Fellowships
    $120,000


    Radioiodide And Pyruvate, A Novel Combined Approach To Breast Cancer Treatment Based On Nis (Na+/I- Symporter) And Smct (Na+/Monocarboxylate Transporter)
    Nancy Carrasco, M.D.
    Cecile Basquin, MD
    Albert Einstein College of Medicine at Yeshiva University
    Postdoctoral Fellowships
    $180,000


    Halofuginone Inhibition Of Tgf-Beta Signaling:Treatment For Bone Metastases
    Theresa Guise, Ph.D.
    Patricia Juarez Camacho, PhD University of Virginia at School of Medicine
    Postdoctoral Fellowships
    $120,000


    The Role Of Tumor-Associated Macrophages In The Metastatic Progression Of Breast Cancer
    Zena Werb*, DVM, Ph.D.
    Kai Kessenbrock, PhD
    University of California at San Francisco
    Postdoctoral Fellowships
    $180,000



    * Pending executed agreement