The following grants were approved by Komen’s national board of directors for FY2011 Research Programs funding, and will be funded upon execution of grant agreements between Komen and the grantee institutions. There are five types (mechanisms) of grants: Career Catalyst Research (CCR), Investigator Initiated Research (IIR), Post Baccalaureate Training in Disparities Research (PBTDR), Postdoctoral Fellowship (PDF), and Promise Grants.

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Select a Project Title for detailed grant information.

Project Title	PI(s)	Organization(s)	State/Country	Affiliate	Research Focus	Mechanism	Amount
A Multi-Gene Assay for the Prognostic Stratification of Ductal Carcinoma in situ	Joseph Geradts, MD	Duke University	NC	NC Triangle Affiliate	Early Detection	IIR	599,998
A Novel Protein that Controls Homologous Recombination in Breast Cancer	Alan D'Andrea, MD (mentor) George-Lucian Moldovan, PhD (fellow)	Dana-Farber Cancer Institute	MA	Massachusetts Affiliate	Biology	PDFBR	$180,000
A Novel Rac-GEF in Breast Cancer	Marcelo Kazanietz, PhD (mentor) Eva Wertheimer, PhD (fellow)	University of Pennsylvania	PA	Philadelphia Affiliate	Etiology	PDFBR	$180,000
A Novel Strategy to Target Breast Cancer Stem cells Utilizing microRNA100	Suling Liu, PhD	University of Michigan	MI	Mid-Michigan Affiliate	Biology	CCR	$450,000
A Transdisciplinary Training Program for Public Health Master and Doctoral Students Wanting to Impact Breast Cancer Disparities	Luisa Franzini, PhD Sally Vernon, PhD	University of Texas at Houston	TX	Houston Affiliate	Prevention	PBTDR	$269,722
Analysis of the Mechanisms that Mediate Cell-cell Adhesion Strengthening and its Importance in Breast Cancer Invasion	Joan Brugge, PhD (mentor) Lisa Gallegos, PhD (fellow)	Harvard University	MA	Massachusetts Affiliate	Biology	PDFBR	$180,000
Angiogenesis-Independent Tumor Penetrating Peptides for Breast Cancer Drug Delivery	Tambet Teesalu, PhD	Burnham Institute	CA	none	Treatment	CCR	$450,000
Blood Based Biomarkers of High Risk and Early Breast Cancer	Samir Hanash, MD, PhD Mary Disis, MD	Fred Hutchinson Cancer Research Center University of Washington	WA	Puget Sound Affiliate	Early Detection	IIR	$599,999
Breast Cancer Risk Stratification in Younger Women: A Combined Baseline Mammography and REIS-based Model	Dror Lederman, PhD	University of Pittsburgh	PA	Pittsburgh Affiliate	Early Detection	CCR	$446,610
Characterization of the Role of Galectins in Mammary Gland Morphogenesis and in Breast Cancer	Mina Bissell, PhD (mentor) Ramray Bhat, PhD (fellow)	Lawrence Berkeley National Laboratory	CA	San Francisco Bay Area Affiliate	Etiology	PDFBR	$177,988
Circulating Folic Acid, DHFR Polymorphism, Multivitamin Use, and Breast Cancer Risk	Anne Zeleniuch-Jacquotte, MD (mentor) Stephanie Scarmo, PhD (fellow)	New York University	NY	Greater New York City Affiliate	Etiology	PDFTR	$120,000
Combinatorial Immunotherapy for Triple-negative Breast Cancer	Soldano Ferrone, MD, PhD (mentor) Yangyang Wang, MD (fellow)	University of Pittsburgh	PA	Pittsburgh Affiliate	Treatment	PDFTR	$180,000
Crosstalk among MED1, ER and HER2: New Strategy to Overcome Endocrine Resistance in Breast Cancer	Xiaoting Zhang, PhD	University of Cincinnati	OH	Greater Cincinnati Affiliate	Treatment	CCR	$450,000
Determining the Molecular Effects of Bisphenol A (BPA) in Mammary Gland Stem Cells and Breast Cancer Proliferation	Susan Krum, PhD	University of California at Los Angeles	CA	Los Angeles County Affiliate	Biology	CCR	$450,000
Development of First-generation Multiplex Metabolomic Biomarker Panel in Serum for Diagnosis and Prognosis of Breast Cancer	Arun Sreekumar, PhD	Medical College of Georgia	GA	none	Early Detection	IIR	$600,000
Development of Novel Therapeutics for the Treatment of Triple-negative Breast Cancer using Targeted Nanoparticle-mediated Delivery of siRNA to Solid Tumors	Frank McCormick, PhD (mentor) Tina Yuan, PhD (fellow)	University of California at San Francisco	CA	San Francisco Bay Area Affiliate	Treatment	PDFBR	$180,000
Development of Synthetic Antigen Binders against Nek3 as a Targeted Therapy in Breast Cancer	Charles Clevenger, MD, PhD (mentor) Christine Ratajczak, PhD (fellow)	Northwestern University	IL	Chicagoland Area Affiliate	Treatment	PDFTR	$180,000
Development of Targeted “Smart” Particles for Silencing the Metastases of Breast Cancer	Mohamed El-Sayed, PhD (mentor) Sofia Merajver, MD, PhD (mentor) Yasemin Yuksel Durmaz, PhD (fellow)	University of Michigan	MI	Mid-Michigan Affiliate	Treatment	PDFTR	$180,000
Disparities in Breast Cancer Outcomes: The Role of Comorbid Conditions and Functional Status	Dejana Braithwaite, PhD	University of California at San Francisco	CA	San Francisco Bay Area Affiliate	Survivorship	CCR	$284,273
Enhancing Efficacy of Chemotherapy in Triple-negative/Basal-like Breast Cancer by Targeting Macrophages	Lisa Coussens, PhD Shelley Hwang, MD, Hope Rugo, MD	University of California at San Francisco	CA	San Francisco Bay Area Affiliate	Biology	PG	$6,500,000
Epigenetic Control of Metastases by the Snail/Slug Transcription Factors	Frank Rauscher, PhD	Wistar Institute	PA	Philadelphia Affiliate	Biology	IIR	$599,999
Evaluating the Role of Anthrax Toxin Receptor 2 in the Myoepithelium During Breast Cancer Progression	Jan Kitajewski, PhD (mentor) Claire Reeves, PhD (fellow)	Columbia University	NY	Greater New York City Affiliate	Biology	PDFBR	$180,000
Evaluation and Development of Breast Cancer Risk Prediction Models among African-American Women	Lynn Rosenberg, ScD (mentor) Deborah Boggs, ScD (fellow)	Boston University	MA	Massachusetts Affiliate	Etiology	PDFDR	$178,191
Evaluation of Genetic Risk in Caribbean Women with Breast and Ovarian Cancer	Judith Hurley, MD	University of Miami	FL	Miami/Ft. Lauderdale Affiliate	Etiology	IIR	$599,997
Evaluation of Novel Serum Biomarkers for Hispanic Women with Breast Cancer	Nita Maihle, PhD	Yale University	CT	Connecticut Affiliate	Early Detection	PBTDR	$270,000
Examining the Role of COX-2 in Initiation and Progression of Post-partum Breast Cancer	Pepper Schedin, PhD (mentor) Virginia Borges, MD (mentor) Traci Lyons, PhD (fellow)	University of Colorado	CO	Denver Metropolitan Affiliate	Biology	PDFBR	$120,000
Functional Study of UBLCP1, A Novel Proteasome-interacting Phosphatase, in Breast Cancer	Jack Dixon, PhD (mentor) Xing Guo, PhD (fellow)	University of California at San Diego	CA	San Diego Affiliate	Biology	PDFBR	$180,000
Germline Mutations in Genes that Modify Epigenetic Silencing in Familial Breast Cancer	Georgia Chenevix-Trench, PhD Kum Kum Khanna, PhD	Queensland Institute of Medical Research	Australia	none	Biology	IIR	$585,265
Gli1 in the Development and Persistence of Micrometastases of Breast Cancer	Andra Frost, MD	University of Alabama at Birmingham	AL	North Central Alabama Affiliate	Biology	IIR	$600,000
Hedgehog Signaling in Breast Cancer: Tumor-stroma Interactions and the Growth of Tumor-Initiating Cells	Philip Beachy, PhD (mentor) Michael Clarke, MD (mentor) Chen Zhao, PhD (fellow)	Stanford University	CA	San Francisco Bay Area Affiliate	Treatment	PDFTR	$180,000
HIF-1 and Extracellular Matrix Composition in Breast Cancer	Gregg Semenza, MD, PhD (mentor) Daniele Gilkes, PhD (fellow)	Johns Hopkins University	MD	Maryland Affiliate	Biology	PDFBR	$180,000
Identification of Key Tumor Suppressor Genes in the Breast Cancer Genome as Biomarkers of Response to Chemotherapy or Prognosis	Jerry Shay, PhD (mentor) Stina Singel, MD, PhD (fellow)	University of Texas at Southwestern Medical Center at Dallas	TX	Dallas County Affiliate	Biology	PDFCR	$180,000
Identification of Lapatinib Resistance Genes in HER2 Positive Breast Cancers using Genome-wide RNAi Technologies	Thomas Westbrook, PhD (mentor) C. Kent Osborne, MD (mentor) Christopher Bland, PhD (fellow)	Baylor College of Medicine	TX	Houston Affiliate	Biology	PDFBR	$180,000
Imaging Breast Cancer with Tc-99m Labeled Acridines by Targeting Telomere/Telomerase Complex	Shuang Liu, PhD (mentor) Yang Zhou, PhD (fellow)	Purdue University	IN	Central Indiana Affiliate	Early Detection	PDFBR	$180,000
Immune and Collagen Basis of Breast Cancer Risk	Shelley Hwang, MD Lisa Coussens, PhD	University of California at San Francisco	CA	San Francisco Bay Area Affiliate	Etiology	IIR	$599,996
Immune Biomarkers of Breast Cancer Risk in Benign Breast Tissue	Amy Degnim, MD	Mayo Clinic and Foundation, Rochester	MN	Minnesota Affiliate	Early Detection	IIR	$600,000
Immune-based Suppression of Breast Cancer Metastasis by Targeting IDO	Alexander Muller, PhD	Lankenau Institute for Medical Research	PA	Philadelphia Affiliate	Biology	IIR	$599,774
Impact of the miR-26 Family of microRNAs on the Stromal-epithelial Dialogue in Breast Cancer	Thomas Duchaine, PhD (mentor) Morag Park, PhD (mentor) Carine Lussier, PhD (fellow)	McGill University	Canada	none	Biology	PDFBR	$180,000
Improving Microcalcification Reconstruction in Digital Tomosynthesis Mammography for Early Detection of Breast Cancer	Heang-Ping Chan, PhD (mentor) Yao Lu, PhD (fellow)	University of Michigan	MI	Mid-Michigan Affiliate	Early Detection	PDFBR	$180,000
Inhibiting the Emergence of Endocrine Resistance in Women with Estrogen Receptor-positive Metastatic Breast Cancer	Luke Whitesell, MD Nancy Lin, MD	Whitehead Institute for Biomedical Research Dana-Farber Cancer Institute	MA	Massachusetts Affiliate	Treatment	IIR	$600,000
Inhibition of Metastatic Breast Cancer by Angiotensin-(1-7)	Elisabeth Tallant, PhD Patricia Gallagher, PhD	Wake Forest University	NC	North Carolina Triad Affiliate	Biology	IIR	$600,000
Molecular Marker Signature Prognostic of Metastatic Disease in Node-negative ER-negative Breast Cancer with no Systemic Therapy	Christopher Umbricht, MD, PhD	Johns Hopkins University	MD	Maryland Affiliate	Biology	IIR	$599,353
Molecular Mechanisms of Snail-induced Epithelial-mesenchymal Transition	Alexey Ivanov, PhD	West Virginia University	WV	West Virginia Affiliate	Biology	CCR	$450,000
Multilevel Determinants of Breast Density in African-American, Hispanic, and White Women	Parisa Tehranifar, DrPH	Columbia University	NY	Greater New York City Affiliate	Etiology	CCR	$448,742
New Strategies for Monitoring Response to Breast Cancer Therapy using Photoacoustic Molecular Imaging	Sanjiv Gambhir, MD, PhD (mentor) Dominique Van de Sompel, PhD (fellow)	Stanford University	CA	San Francisco Bay Area Affiliate	Early Detection	PDFTR	$180,000
New Tools for Studying the Biology of BRCA1	Eric Strieter, PhD	University of Wisconsin at Madison	WI	Madison Affiliate	Biology	CCR	$447,705
Novel Estrogen Receptor Modulators to Treat Endocrine Therapy Resistant Hormone Receptor Positive Breast Cancers	Rajeshwar Tekmal, PhD Ratna Vadlamudi, PhD	University of Texas Health Science Center at San Antonio	TX	San Antonio Affiliate	Treatment	IIR	$600,000
Personalized Breast Cancer Vaccines Based on Genome Sequencing	William Gillanders, MD, Ted Hansen, PhD and Elaine Mardis, PhD	Washington University at St. Louis	MO	St. Louis Affiliate	Prevention	PG	$6,500,000
PI3K/Akt Isoforms and PTEN Signaling in Breast Cancer Invasive Migration	Alex Toker, PhD (mentor) Emilie Collmann, PhD (fellow)	Beth Israel Deaconess Medical Center	MA	Massachusetts Affiliate	Biology	PDFBR	$180,000
Preclinical Development of a PEA-15-Based Therapy for Triple-Negative Breast Cancer	Chandra Bartholomeusz, MD, PhD (mentor) Xuemei Xie, PhD (fellow)	University of Texas M.D. Anderson Cancer Center	TX	Houston Affiliate	Treatment	PDFTR	$180,000
Predicting Response to Neoadjuvant Chemotherapy using Optical Tomographic Imaging in Women with Breast Cancer	Dawn Hershman, MD (mentor) Emerson Lim, MD (fellow)	Columbia University	NY	Greater New York City Affiliate	Early Detection	PDFCR	$120,000
Predictors and Mechanisms of Relapse after Aromatase Inhibitor Therapy: Targeting IL-6 and STAT3	Angela DeMichele, MD	University of Pennsylvania	PA	Philadelphia Affiliate	Early Detection	IIR	$600,000
Progesterone Receptor Interactions with Cell Cycle Regulatory Molecules Promote Breast Tumor Initiation and Progression.	Carol Lange, PhD (mentor) Gwen Dressing, PhD (fellow)	University of Minnesota at Twin Cities	MN	Minnesota Affiliate	Biology	PDFBR	$180,000
Promoting Regular Screening Mammography in an American Indian Community in Oklahoma	Eleni Tolma, PhD	University of Oklahoma	OK	Central and Western Oklahoma Affiliate	Survivorship	IIR	$599,966
Racial Disparities in Cardiovascular Morbidity and Mortality Resulting from Aromatase Inhibitors among African-American and Caucasian Breast Cancer Survivors	Lisa Gallicchio, PhD	Mercy Medical Center	MD	Maryland Affiliate	Survivorship	CCR	$448,610
Regulation of Breast Cancer Metastasis by the K63-specific Ubiquitin-conjugating Enzyme Ubc13	Michael Karin, PhD (mentor) Xuefeng Wu, PhD (fellow)	University of California at San Diego	CA	San Diego Affiliate	Biology	PDFBR	$180,000
Role of SCF/Fbxo31 Ubiquitin Ligase Substrates in Cell Cycle Control and Breast Cancer	Michele Pagano, MD (mentor) Shanshan Duan, PhD (fellow)	New York University	NY	Greater New York City Affiliate	Biology	PDFBR	$180,000
Role of Tumor Cell-derived ShcA in Regulating the Adaptive Immune Response during Breast Cancer Progression	Josie Ursini-Siegel, PhD	Jewish General Hospital	Canada	none	Biology	CCR	$449,982
Role of Wnt Signaling and Pygo2 in the Epigenetic Control of Normal and Cancerous Mammary Epithelial Cells	Xing Dai, PhD	University of California at Irvine	CA	Orange County Affiliate	Biology	IIR	$600,000
Strategic Global Mining of Methylated Promoter Sites in a Diverse ER-negative Primary Care Breast Cancer Population	Maria Worsham, PhD	Henry Ford Health System	MI	Komen Detroit Race for the Cure®	Early Detection	IIR	$599,850
Structural Models of Breast Cancer Outcomes Disparities	Terry Hyslop, PhD	Thomas Jefferson University	PA	Philadelphia Affiliate	Early Detection	IIR	$600,000
Targeting VCAM1 to Prevent Metastatic Recurrence from Dormant Bone Micrometastases	Yibin Kang, PhD	Princeton University	NJ	Central and South Jersey Affiliate	Biology	IIR	$588,750
Technology Enhanced Nurse Navigation (TENN): Improving Care, Saving Lives	Kathy Helzlsouer, MD	Mercy Medical Center	MD	Maryland Affiliate	Survivorship	IIR	$599,883
Testing the Role of Non-canonical FAK Signaling in Breast Cancer Metastasis	David Schlaepfer, PhD (mentor) Isabelle Tanjoni, DVM, PhD (fellow)	University of California at San Diego	CA	San Diego Affiliate	Biology	PDFBR	$180,000
The Assessment of the HOXB13:IL17BR+MGI Breast Cancer Biomarker in the BIG 1-98 Cohort	Dennis Sgroi, MD	Massachusetts General Hospital	MA	Massachusetts Affiliate	Early Detection	IIR	$400,000
The Effect of a Dietary Supplement Silibinin on Breast Cancer Tumor Initiating Cells in Inflammatory Breast Cancer	Wendy Woodward, MD, PhD (mentor) Wei Xu, PhD (fellow)	UT M.D. Anderson Cancer Center	TX	Houston Affiliate	Treatment	PDFTR	$120,000
The Massively Parallel Sequencing of Epigenetic Pathway in High-risk Breast Cancer Families	Tomas Kirchhoff, PhD	Memorial Sloan-Kettering Cancer Center	NY	Greater New York City Affiliate	Early Detection	IIR	$600,000
The Molecular Basis of Breast Density and its Implications for Breast Cancer Prevention	Kornelia Polyak, MD, PhD Rulla Tamimi, ScD	Dana-Farber Cancer Institute Brigham and Women's Hospital	MA	Massachusetts Affiliate	Early Detection	IIR	$600,000
The Role of Cytotoxic Tumor Entrained Neutrophils in Inhibiting Metastatic Breast Cancer	Robert Benezra, PhD (mentor) Elizabeth Comen, MD (fellow)	Memorial Sloan-Kettering Cancer Center	NY	Greater New York City Affiliate	Treatment	PDFCR	$120,000
The Warburg Effect Revisited: Does Increased Glucose Uptake in Mammary Cells from African-American Women Predict Aggressive Triple-Negative Breast Cancer?	Victoria Seewaldt, MD (mentor) Nirmala Ramanujam, PhD (mentor) Abigail Hoffman, MD (fellow)	Duke University	NC	NC Triangle Affiliate	Early Detection	PDFCR	$180,000
Toward Novel Drugs for Anti-Estrogen Resistant Breast Cancer	Eliot Rosen, MD, PhD	Georgetown University	DC	Global Race for the Cure®	Treatment	IIR	$600,000
Treatment of Her-2 Overexpressing Breast Cancer with Targeted Immunoliposomes	Thomas Anchordoquy, PhD (mentor) Max Kullberg, PhD (fellow)	University of Colorado at Denver	CO	Denver Metropolitan Affiliate	Treatment	PDFTR	$180,000
Tumor Macrophage-mediated Inflammatory Resolution Limits Endogenous Immune Control of Residual Disease	Michael Gough, PhD	Providence Portland Medical Center	OR	Oregon and SW Washington Affiliate	Treatment	CCR	$449,887
Tumor-derived Jagged1 Promotes Breast Cancer Bone Metastasis by Activating Stromal Notch Signaling	Yibin Kang, PhD (mentor) Hanqiu Zheng, PhD (fellow)	Princeton University	NJ	Central and South Jersey Affiliate	Biology	PDFBR	$180,000
Twist1 and Breast Cancer Micrometastases Dormancy	Gregory Longmore, MD	Washington University at St. Louis	MO	St. Louis Affiliate	Biology	IIR	$600,000
UIC Komen Cancer Epidemiology and Health Disparities Fellowship	Garth Rauscher, PhD Faith Davis, PhD	University of Illinois at Chicago University of Illinois at Chicago School of Public Health	IL	Chicagoland Area Affiliate	Survivorship	PBTDR	$403,119
Vaccine Strategy to Treat and Prevent Resistance to Anti-estrogen Therapy in Breast Cancer	Takuya Osada, MD, PhD	Duke University	NC	NC Triangle Affiliate	Treatment	CCR	$380,048
The Role of Endothelial MicroRNA-126 in Breast Tumor Progression and Angiogenesis	Calvin Kuo, MD, PhD (mentor) Cynthia Kosinski, PhD (fellow)	Standford University	CA	San Francisco Bay Area Affiliate	Biology	PDFBR	$180,000
A Novel Combination Therapy for Triple Negative Breast Cancer: Erlotinib And Metformin	Matthew Maurer, MD	Columbia University	NY	Greater New York City Affiliate	Treatment	CCR	$450,000
Development of an individualized risk prediction model for women with atypical hyperplasia	Derek Radisky, PhD Lynn Hartmann, MD	Mayo Clinic and Foundation Mayo Clinic and Foundation	FL MN	North Florida Affiliate Minnesota Affiliate	Early Detection	IIR	$597,939
Development of Pin1 inhibitors to treat aggressive and/or drug-resistant breast cancers	Kun Ping Lu, MD, PhD (mentor) Shuo Wei, PhD (fellow)	Beth Israel Deaconess Medical Center	MA	Massachusetts Affiliate	Treatment	PDFTR	$180,000
Ecdysoneless, a novel regulator of breast cancer cell proliferation	Vimla  Band, PhD (mentor) Sameer Mirza, PhD (fellow)	University of Nebraska	NE	Nebraska Affiliate	Biology	PDFBR	$180,000
FACBC PET as a Staging Tool and Indicator of Therapeutic Response in Breast Cancer Patients	Gary Ulaner, MD, PhD	Memorial Sloan-Kettering Cancer Center	NY	Greater New York City Affiliate	Early Detection	CCR	$300,000
Genomic signatures to guide breast cancer analysis and personalize therapy	Eran Andrechek, PhD	Michigan State University	MI	Mid-Michigan Affiliate	Biology	CCR	$450,000
GREB1: A Novel Prognostic and Therapeutic Target in Breast Cancers with Resistance to Endocrine Therapies	Marc Lippman, MD H. James Hnatyszyn, PhD	University of Miami	FL	Miami/Ft. Lauderdale Affiliate	Early Detection	IIR	$600,000
Identifying the Missing Heritability of Breast Cancer.	Melissa Southey, PhD (mentor) Tu Nguyen-Dumont, PhD (fellow)	University of Melbourne	Australia	none	Biology	PDFBR	$180,000
Investigating the signaling pathways involved in the ECM degradation by breast cancer cells.	John Condeelis, PhD (mentor) Ved Sharma, PhD (fellow)	Albert Einstein College of Medicine at Yeshiva University	NY	Greater New York City Affiliate	Biology	PDFBR	$180,000
Mechanisms of cell migration and invasion in aggressive breast cancer	Morag Park, PhD (mentor) Kossay Zaoui, PhD (fellow)	McGill University	Canada	none	Biology	PDFBR	$180,000
Rational Molecular Multi-targeting in High-risk Breast Cancer	Kevin Kozak, MD, PhD	University of Wisconsin	WI	Madison Affiliate	Treatment	CCR	$450,000
Role of lymph node lymphangiogenesis and VEGF-C in the progression of micrometastases	Mihaela Skobe, PhD	Mount Sinai School of Medicine	NY	Greater New York City Affiliate	Biology	IIR	$600,000
Specific detection of metastases of breast cancer and imaging response to IGF-1R drugs by MRI	Deepali Sachdev, PhD	University of Minnesota at Twin Cities	MN	Minnesota Affiliate	Early Detection	IIR	$599,975
Targeted Therapies for Breast Cancer	E. Premkumar Reddy, PhD (mentor) Sai Krishna Athuluri Divakar, PhD (fellow)	Mount Sinai School of Medicine	NY	Greater New York City Affiliate	Treatment	PDFTR	$180,000
Targeted therapy for micrometastatic minimal residual disease to prevent breast cancer recurrence	Lewis Chodosh, MD, PhD	University of Pennsylvania	PA	Philadelphia Affiliate	Biology	IIR	$600,000
Targeting breast cancer stem cells by blocking both intrinsic (Akt) and extrinsic (IL-6) signaling pathways in metastatic mouse xenograft models	Hasan Korkaya, DVM, PhD	University of Michigan	MI	Mid-Michigan Affiliate	Biology	CCR	$450,000
Targeting stem and myoepithelial cells with nutritional compounds to prevent breast cancer in women with high risk ductal carcinoma in situ	Madhuri Kakarala, MD, PhD	University of Michigan	MI	Mid-Michigan Affiliate	Prevention	CCR	$450,000
The Breast Cancer Microenvironment Promotes Angiogenesis through Inhibition of TGF-beta Signaling in Endothelial Cells	Gerard Blobe, MD, PhD (mentor) Hongyu  Tian, PhD (fellow)	Duke University	NC	NC Triangle Affiliate	Biology	PDFBR	$180,000
The Role of Separase in Centrosome Duplication and Genome Stability	Tim Stearns, PhD (mentor) Erkang Ai, PhD (fellow)	Stanford University	CA	San Francisco Bay Area Affiliate	Biology	PDFBR	$178,225
The role of SLIT/ROBO signaling in generation of breast cancer stem cells	Lindsay Hinck, PhD (mentor) Gwyndolen Harburg, PhD (fellow)	University of California at Santa Cruz	CA	none	Etiology	PDFBR	$180,000
The Use of 2ME2 as a Novel and Effective Therapy for the Treatment of Endocrine Resistant Breast Cancer Growth, Metastasis and Tumor-induced Bone Osteolysis	Muzaffer Cicek, PhD	Mayo Clinic and Foundation	MN	Minnesota Affiliate	Treatment	CCR	$450,000
Tumor-selectively replicating retrovirus vectors for gene therapy of breast cancer CNS metastasis	Noriyuki Kasahara, MD, PhD (mentor) Akihito Inagaki, PhD (fellow)	University of California at Los Angeles	CA	Los Angeles County Affiliate	Treatment	PDFTR	$180,000

Career Catalyst Research (CCR)
CCR grants provide unique opportunities for scientists in the early stages of their career to achieve research independence. Scientific focus on biology and translation research and disparities research.

• Applicants may request funding for 2 or 3 years:
• Up to $300,000 for the initial 2 years; with $150,000 for a 3rd year based on 1st year progress.

Investigator Initiated Research (IIR)
IIR grants seek to stimulate exploration of new ideas and novel approaches in breast cancer research and clinical practice that will lead to reductions in breast cancer incidence and mortality within the next decade.
Scientific focus on molecular predictors of high risk and early disease; targeted therapies for hormone receptor positive breast cancer with resistance to endocrine therapy; biologic underpinnings and therapeutic implications of metastases; epigenetic alterations; and disparities research.

• Applicants may request funding for 2 or 3 years:
• Up to $400,000 over 2 years; or up to $600,000 over 3 years

Post Baccalaureate Training in Disparities Research (PBTDR)
PBTDR grants seek to support training for students very early in their careers to allow them to begin to define meaningful career paths focused on disparities in breast cancer outcomes across population groups.

•  Up to $45,000 per student (up to 3), per year for 2 years, with a progress-based option for a 3rd year.

Postdoctoral Fellowship (PDF)
PDF grants seek to attract scientists into careers addressing important research questions about breast cancer, expand the skills and expertise of breast cancer researchers in training, and position trainees for independent careers conducting breast cancer research that will directly affect breast cancer patients.
Fellowships are awarded to the mentor/PI.  By the start date of the grant, fellows must be no more than 3 years post-completion of his/her most recent clinical M.D. fellowship or 5 years post-completion of his/her most recent M.D. residency or Ph.D.
Scientific focus on basic (PDFBR), translational (PDFTR), clinical (PDFCR) and disparities (PDFDR) research.

• Applicants may request funding for 2 or 3 years:
• Up to $60,000 per year for the initial 2 years; with $60,000 for a 3rd year based on 1st year progress.

Promise Grant (PG)
Promise Grants seek to support integrated programs of collaborative and cross-disciplinary research projects leading to the aggressive translation of scientific discoveries into interventions and strategies that have the greatest potential to significantly reduce breast cancer incidence and/or mortality.

• Applicants may request funding for 5 years:
• Up to $6,500,000 over the timeframe of the grant.